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CompletedNCT05190874Updated Apr 7, 2022

Grappler Interference Screw Post-Market Collection of Patient Reported Outcome Measures

An observational study in Ankle Injuries, Syndesmotic Injuries and Ankle Inversion Sprain, sponsored by Paragon 28. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2022-04-07.

Sponsored by Paragon 28 · Observational

Study type
Observational
Model
Case-only
Time perspective
Other
Enrollment
19
Sex
All
01

Study summary

Ambispective, multi-surgeon, single site, consecutive case series to determine the safety, performance, and benefits of the Grappler(R) Interference Screw.

Read the detailed description

This is an ambispective, multi-surgeon, single site, consecutive case series taking place in the United States. Once a subject is identified and informed consent is obtained from that subject, retrospective data will be collected from the subject's electronic medical record (EMR), and prospective data will be collected from subject-provided PROM's. A minimum of 16 and maximum of 23 subjects will participate in the study.

02

Conditions studied

  • Ankle Injuries
  • Syndesmotic Injuries
  • Ankle Inversion Sprain
  • Deltoid Ankle Sprain
  • Achilles Tendon Rupture
  • Flexor Hallucis Longus on the Left
  • Flexor Hallucis Longus on the Right
  • Flexor Digitorum Longus on the Left
  • Flexor Digitorum Longus on the Right
  • Ankle Sprains
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The investigational population will include a minimum of 23 subjects who have undergone a foot and/or ankle procedure that fulfill the eligibility criteria

Inclusion criteria

  • The subject underwent a foot and/or ankle procedure involving soft tissue attachment to bone using the Grappler Interference Screw System and completed by one of the designated investigators who are experienced in the use of such implants and the required specialized surgical techniques
  • The subject signs a written informed consent form (ICF)

Exclusion criteria

Exclusion Criteria:

  • None
04

Study design

Observational model
Case-only
Time perspective
Other
Enrollment
19 participants (actual)
Patient registry
No

Groups and cohorts

  • Device: Grappler Interference Screw System

    Foot and/or ankle procedure involving soft tissue attachment to bone using the Grappler Interference Screw System

    Device: Grappler Interference Screw System

Interventions

  • DeviceGrappler Interference Screw System

    Foot and/or ankle procedure involving soft tissue attachment to bone using the Grappler® Interference Screw System

05

What researchers measure

Primary outcomes

  1. Device performance and benefits as related to Foot and Ankle Mobility Measure

    Device performance and benefits as related to Foot and Ankle Mobility Measure Activities of Daily Living (0-84) and sports (0-32) subscales. The higher the score, the higher the level of function, with 100% representing no dysfunction.

    Time frame: 6 months post-operative

  2. Device performance and benefits as related to pain levels based on the Visual Analog Scale

    Device performance and benefits as related to pain levels based on the Visual Analog Scale (range: 0 to 100; 0 = no pain; 100 = worst pain imaginable)of Daily Living (0-84) and sports (0-32) subscales. The higher the score, the higher the level of function, with 100% representing no dysfunction.

    Time frame: 6 months post-operative

  3. Device performance and benefits as related to pain levels based on Patient satisfaction

    Device performance and benefits as related to patient satisfaction (very satisfied, good, fair, not satisfied)

    Time frame: 6 months post-operative

Secondary outcomes

  1. Safety will be assessed by recording the incidence of secondary procedures related to the index device

    Safety will be assessed by recording the incidence of secondary procedures related to the index device

    Time frame: 6 months post-operative

06

Study locations

1 site
  • Orthopedic Foot and Ankle
    Worthington, Ohio 43085, United States
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT05190874
Lead sponsor
Paragon 28
Responsible party
Sponsor
First posted
Jan 13, 2022
Start date
Jan 14, 2022
Primary completion
Mar 11, 2022
Completion
Apr 6, 2022
Last update
Apr 7, 2022

Study contacts

Jacy Legue
study director · Paragon 28

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.

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