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CompletedNCT05058235Updated Sep 27, 2021

Comparison of Active Release Technique and Bent Leg Raise In Osteoarthritis.

An interventional study of Active Release Technique and Bent leg raise in Knee Osteoarthritis, sponsored by Riphah International University. Completed at 2 sites in Pakistan. Open to participants aged 45 Years to 60 Years. Per ClinicalTrials.gov, last updated 2021-09-27.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 9 months after the study started (first participant enrolled Nov 2020, registered Aug 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
48
Allocation
Randomized
Ages
45 Years to 60 Years
Sex
All
01

Study summary

The objective of the study was to compare the effects of active release technique and bent leg raise on hamstring flexibility, functional outcomes, and pain in patients with knee osteoarthritis.

Read the detailed description

Knee Osteoarthritis is a common progressive degenerative joint disease. Muscular weakness and other structural abnormalities can cause low back pain. Hamstring muscle being a postural muscle has an increased tendency to become tight. In this study, participants with knee osteoarthritis having hamstring tightness were included. Active Release Technique and Bent Leg Raise technique have been used to increase flexibility in hamstrings in these patients with knee osteoarthritis.

02

Conditions studied

  • Knee Osteoarthritis

Keywords

  • Active Release Technique
  • Bent leg raise
  • Hamstring flexibility
03

In context

Osteoarthritis

4,398 studies on the registry are indexed under Osteoarthritis; 583 are open to participants now.

This study's enrollment of 48 is below the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.

Browse Osteoarthritis studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
45 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Diagnosed patients of Knee Osteoarthritis
  • Hamstring length less than 160 degrees
  • Minimum history of 3 months
  • Willing to participate

Exclusion criteria

Exclusion Criteria:

  • Patients who have passive knee extension more than 160 degrees
  • Patients with less than 3 months history
  • Patients who have osteoarthritis of other than the knee joint
  • Patients with history of fracture
  • Patients with post surgical history
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
48 participants (actual)

Study arms

  • Experimental
    Active Release Technique

    Hot pack, TENS, Quadriceps Isometric strengthening, Active Release Technique

    Other: Active Release Technique

  • Active comparator
    Bent leg raise

    Hot pack, TENS, Quadriceps Isometric strengthening, Bent leg raise

    Other: Bent leg raise

Interventions

  • OtherActive Release Technique

    Moist Hot pack 10 mins/1 set/ (6 days/ week), TENS 20 mins/1 set/ (6 days/ week), Quadriceps Isometric Strengthening 5 sec hold, 10 reps/ 1 set/(6 days/ week), Active release Technique 5 reps/ 1 set/ (6 days/ week) A total of 2 weeks (12 sessions, 6 sessions/ week) were given each consisting of 40 mins.

  • OtherBent leg raise

    Moist Hot pack 10 mins/1 set/ (6 days/ week), TENS 20 mins/1 set/ (6 days/ week), Quadriceps Isometric Strengthening 5 sec hold, 10 reps/ 1 set/(6 days/ week), Bent leg raise 5 sec hold/ 5 sec stretch/ 3 reps/ 1 min rest interval/ 1 set/ (6 days/ week). A total of 2 weeks (12 sessions, 6 sessions/ week) were given each consisting of 40 mins.

06

What researchers measure

Primary outcomes

  1. Hamstring flexibility

    Changes from baseline, Hamstring flexibility was measured through passive knee extension test with the help of Goniometer. Normal value of knee extension angle is 180 degrees. Values decreased than 160 degree represents hamstring tightness.

    Time frame: 12 days

Secondary outcomes

  1. Functional outcome

    Changes from baseline, Functional outcome was taken through western Ontario McMaster Universities Osteoarthritis Index tool. It comprises three sections containing 24 items. Score ranges from 0 to 96. 0 representing a healthy state and higher scores indicating worst health.

    Time frame: 12 days

  2. Pain on Visual analogue Scale

    Changes from baseline, Pain was measured through Visual Analogue Scale. It comprises of a continuous scale of 10cm line. 0 to 4mm represents "no pain", 5mm to 44mm indicates "mild pain", whereas 45mm to 74mm indicates "moderate pain" and continues to the range of "worst pain" between 75mm to 100 mm.

    Time frame: 12 days

07

Study locations

2 sites
  • Noor Physio and Sports Injury Clinic, G-8 Markaz
    Islamabad, Federal 44000, Pakistan
  • Riphah Rehabilitation Center, Westridge campus, Potohar Tower, Peshawar Road
    Rawalpindi, Punjab 46000, Pakistan
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 27, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05058235
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Sep 27, 2021
Start date
Nov 14, 2020
Primary completion
Apr 20, 2021
Completion
Apr 30, 2021
Last update
Sep 27, 2021

Study contacts

Asghar Khan, Phd
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2021. You cannot join it, but the record below documents what was studied.

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