An observational study in Heart; Dysfunction Postoperative, Cardiac Surgery, Right Heart Failure and Right Ventricular Dysfunction, sponsored by Montreal Heart Institute. Completed at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-03-19.
Sponsored by Montreal Heart Institute · Observational
Among 22 studies in Heart Failure by Montreal Heart Institute — 4 open to participants now, 4 under way, none of them phase 3. Heart Failure · Montreal Heart Institute.
Among the 22 studies in Heart Failure by Montreal Heart Institute, this one is one of 3 that started in 2021, is one of 6 observational ones, and was the 19th registered.
6,331 studies on the registry are indexed under Heart Failure; 1,396 are open to participants now.
This study's enrollment of 150 is below the median of 200 across 1,983 observational studies indexed under Heart Failure.
Browse Heart Failure studies →4 of the 22 studies in Heart Failure by Montreal Heart Institute are open now, in 1 country. Each count lists the studies.
Of the 968 Heart Failure studies recruiting now, 691 (71%) set no upper age limit and 89 (9%) stop at 75 or younger; 64 take children under 18; 96 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →22 studies; the count open now beside each. This study's row is marked.
First in 2001; this study’s year is marked. 3 started in 2021.
Median enrollment 120 across the 15 interventional studies, 146 across the 7 observational. Of the 15 that completed or were terminated, 0 (0%) have results posted.
Montreal Heart Institute is the lead sponsor of 101 studies on the registry; 24 are open to participants now.
1 of the studies in Heart Failure by Montreal Heart Institute that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT04970888Montreal Heart InstituteComparing the Effects of Combining Cognitive and Physical Exercise Training on Cognition, and Cerebral Blood Flow Regulation in Men and Women With Chronic Heart Failure | 2026-12-01 |
Among the 22 studies in Heart Failure by Montreal Heart Institute, from their registry updates:
Nothing recorded among them since 2026-09-25.
Right heart failure during cardiac surgery is associated with increased perioperative morbidity and mortality. In this context, it is imperative to develop simple diagnostic tools to detect right heart failure. The purpose of this observational study is to determine if ultrasound Doppler of the femoral vein can detect and predict right ventricular failure after cardiac surgeries requiring cardiopulmonary bypass. It is expected that an elevated pulsatility of the femoral vein before the induction of general anesthesia is associated with perioperative right heart failure.
Adults undergoing elective cardiac surgery at the Montreal Heart Institute which requires cardiopulmonary bypass and perioperative trans oesophageal echography
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Adults undergoing general anesthesia for an elective cardiac surgery requiring cardiopulmonary bypass
Determine the prevalence of an elevated pulsatility of the femoral vein on Doppler ultrasound before the induction of general anesthesia
An elevated pulsatility on Doppler ultrasound is defined as a biphasic signal of the femoral vein with a retrograde velocity \> 10 cm/s on a long axis view at an angle correction \< 60 degrees. If there's signs of cardiac modulation on the Doppler ultrasound, pulsatility index will be measured in long and short axis as followed : (maximal velocity - minimal velocity)/maximal velocity.
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine the association between an elevated femoral vein pulsatility and diastolic or systolic right ventricular failure, before and after cardiac surgery and at the intensive care unit
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine the association between an elevated femoral vein pulsatility and the intracardiac pressures of the right heart cavities and the pulmonary artery
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine the association between the prevalence of an elevated femoral vein pulsatility and the portal vein pulsatility
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine the impact of positive-pressure ventilation on the femoral vein pulsatility
Time frame: After induction of anesthesia and before cardiopulmonary bypass.
Determine the association between a preoperative elevated femoral vein pulsatility and postoperative complications.
Postoperative complications will be defined as prolonged mechanical ventilation, inotropes or vasopressors dependencies, surgical second-look, acute kidney injury, mortality, hemorrhage, surgical sites infections, delirium and strokes
Time frame: Immediate postoperative to Day 1 postoperatively at the intensive care unit
Compare right and left femoral vein Doppler's ultrasound
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine the most valid measure between long and short axis ultrasound of the femoral vein, and their respective sensibility and specificity to predict complications
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine the sensibility and specificity of the values obtained by the femoral vein Doppler ultrasound to predict postoperative complications
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine if the diameter of the femoral vein as a useful predictor of right heart failure or of post-operative complications
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Determine the association between an elevated femoral vein pulsatility and postoperative delirium (as evaluated by the Intensive Care Delirium Screening Checklist)
Time frame: Before induction of anesthesia to day 1 postoperatively at the intensive care unit
Plan to share: Undecided
This study is completed, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.
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