An observational study in Cleft Lip and Palate and Bone Graft; Complications, sponsored by Chang Gung Memorial Hospital. Completed at 1 site in Taiwan. Open to participants aged 8 Years to 10 Years. Per ClinicalTrials.gov, last updated 2021-08-12.
Sponsored by Chang Gung Memorial Hospital · Observational
The cleft patients received alveolar bone graft(ABG) for alveolar defect. Body mass index (BMI) was measured for each patients when receiving ABG. Bone mineral density was measured by Cone-Beam CT at two time-points: post-ABG six months, and post-ABG two years. The study was to analyze the correlation between BMI and post-operative bone mineral density.
Although childhood obesity is a growing issue, the association between BMI and the progressive bone mineral density (BMD) in grafted tissue after secondar alveolar grafting (ABG) remains little reviewed. This study compared the correlation between BMI and the progressive BMD after ABG procedure. Thirty-nine patients with unilateral or bilateral clefts were enrolled. ABG was performed at mixed-dentition age. Patient were classified into underweight, normal weight, and overweight or obese based on age- and sex-adjusted BMI. BMD was expressed in Hounsfield unit (HU) on cone-beam computed tomography (CBCT), which was obtained at 6 months (T1) and 2 years (T2) postoperatively. Calibrated BMD (HUgrafted tissue/HUpogonion¬, BMDc) was used for further analysis.
162 studies on the registry are indexed under Cleft Lip; 51 are open to participants now.
This study's enrollment of 39 is below the median of 100 across 45 observational studies indexed under Cleft Lip.
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the patients with unilateral and bilateral cleft lip and palate received alveolar bone graft at their 9 year of age.
Exclusion Criteria:
alveolar bone grafting was performed when the cleft patients were aged around 9 years old. CBCT was used to analyze the bone mineral density of grafted tissue.
Procedure: alveolar bone grafting
the surgery of alveolar bone graft for alveolar defect in cleft patients
bone mineral density
measuring the bone density from cone beam CT
Time frame: post-ABG six months
bone mineral density
measuring the bone density from cone beam CT
Time frame: post-ABG two years
Plan to share: No — no plan shared.
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This study is completed, as verified in Aug 2021. You cannot join it, but the record below documents what was studied.
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Chang Gung Memorial Hospital