A Phase 4 interventional study of Injection of dextrose, local anesthetic and saline to the myofascial trigger point and Local anesthetic and saline injection to the myofascial trigger point in Efficacy of Dextrose Prolotherapy in Myofascial Pain Syndrome, sponsored by Mustafa Kemal University. Status unknown at 1 site in Turkey. Open to female participants aged 20 Years to 50 Years. Per ClinicalTrials.gov, last updated 2021-07-21.
Sponsored by Mustafa Kemal University · Phase 4, Interventional, and Treatment
Myofascial pain syndrome is characterized by the presence of hypersensitive points called trigger points that cause pain, tenderness, spasm, stiffness, limitation of movement, weakness, taut band within the muscle, and pain reflected by pressing in a muscle group or a single muscle.
Prolotherapy is a regenerative treatment method in the treatment of chronic musculoskeletal pain, in which an irritating solution is injected, often hypertonic dextrose, into painful ligament and tendon attachments and adjacent joint spaces.
In this study, it was aimed to examine the effect of prolotherapy application on pain, neck range of motion and neck disability in women with myofascial pain syndrome.
1,136 studies on the registry are indexed under Myofascial Pain Syndromes; 137 are open to participants now.
This study's planned enrollment of 60 is close to the median of 60 across 931 interventional studies indexed under Myofascial Pain Syndromes.
Browse Myofascial Pain Syndromes studies →Mustafa Kemal University is the lead sponsor of 71 studies on the registry; 18 are open to participants now.
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Exclusion Criteria:
Only saline and local anesthetic (lidocaine)
Drug: Local anesthetic and saline injection to the myofascial trigger point
Dextrose, saline and local anesthetic (lidocaine)
Drug: Injection of dextrose, local anesthetic and saline to the myofascial trigger point
An injection of 5 ml of 5% dextrose prolotherapy using 2.5 ml 10% dextrose, 1 ml 2% local anesthetic (lidocaine), 1.5 ml 0.9% saline will be administered to the active group from at least 10 trigger points.
A total of 5 ml of solution created by using 4 ml of 0.9% saline and 1 ml of 2% local anesthetic (lidocaine) will be administered to the control group, with at least 10 trigger points.
Visual Analog Scale
0-10 cm visual scale (0: no pain, 10: most severe pain)
Time frame: First month post-treatment
Neck Disability Index
It measures the functional state of the neck by scoring between 0-5 points according to the severity of pain, consisting of 20 questions.
Time frame: First month post-treatment
Neck joint range of motion measurement
Active neck range of motion, which shows the movement of the neck in all directions, is evaluated by goniometric measurement.
Time frame: First month post-treatment
Side effects
Edema, ecchymosis, hematoma, allergic reaction, exacerbation of pain, systemic or distant side effects
Time frame: Through study completion, an average of 6 month.
This study is status unknown, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.
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Mustafa Kemal University