An interventional study of Ischemic release and Sustained pressure Direct Myofascial release in Trigger Point Pain, Myofascial, sponsored by Foundation University Islamabad. Recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 35 Years. Per ClinicalTrials.gov, last updated 2026-10-05.
Sponsored by Foundation University Islamabad · Not applicable, Interventional, and Treatment
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Among 32 studies in Myofascial Pain Syndromes with a site in Pakistan — 10 open to participants now, 12 under way, none of them phase 3. Myofascial Pain Syndromes · Pakistan.
Among the 32 studies in Myofascial Pain Syndromes with a site in Pakistan, this one is the 14th largest by planned enrollment, is one of 7 that started in 2026, is one of 32 with no phase, reaches primary completion later than 9 of the 11 other live ones, and was the 31st registered.
339 studies on the registry are indexed under Myofascial Pain Syndromes; 66 are open to participants now.
Browse Myofascial Pain Syndromes studies →10 of the 32 studies in Myofascial Pain Syndromes with a site in Pakistan are open now. Recruiting first, the newest first:
Riphah International University · Sites in Pakistan
Ages 18–35
Foundation University Islamabad · Sites in Pakistan
Ages 18–25
University of Faisalabad · Sites in Pakistan
Ages 18–30 · Women only
National Orthopedic and General Hospital · Sites in Pakistan
Ages 20–40
Riphah International University · Sites in Pakistan
Ages 25–50
A study can be open while its sites in Pakistan have not opened yet or have stopped. Only those recruiting at a site in Pakistan →
Of the 34 Myofascial Pain Syndromes studies recruiting now, 5 (15%) set no upper age limit and 26 (76%) stop at 75 or younger; 2 take children under 18; 4 take healthy volunteers.
This study: 18 Years to 35 Years · all sexes · no healthy volunteers.
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32 studies; the count open now beside each. This study's row is marked.
First in 2018; this study’s year is marked. 7 started in 2026.
This study's planned enrollment of 42 is below the median of 50 across 307 interventional studies indexed under Myofascial Pain Syndromes.
Median enrollment 37 across the 32 interventional studies. Of the 19 that completed or were terminated, 0 (0%) have results posted.
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None of the 32 has an industry lead sponsor. The 10 most frequent:
Foundation University Islamabad is the lead sponsor of 255 studies on the registry; 142 are open to participants now.
Foundation University Islamabad has 2 studies filed under Myofascial Pain Syndromes — fewer than ten, so there is no comparison to draw.
3 of the studies in Myofascial Pain Syndromes with a site in Pakistan that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07904559University of LahoreComparing Instrument-Assisted Soft Tissue Mobilization and Muscle Energy Technique for Myofascial Pain Syndrome in Women | 2026-12 |
| NCT07573527Riphah International UniversityEffectiveness of Tele-Rehabilitation in Managing Rhomboid Trigger Points in Patients With Myofascial Pain Syndrome | 2026-12 |
| NCT07838584Foundation University IslamabadComparison of Ischemic Release and Sustained Pressure Direct Myofascial Release in Upper Trapezius Trigger Point | 2026-12-18 |
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Among the 32 studies in Myofascial Pain Syndromes with a site in Pakistan, from their registry updates:
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This randomized controlled trial aims to compare the clinical effectiveness of ischemic release and sustained pressure direct myofascial release for upper trapezius trigger points.
The study will compare their effects on pain pressure threshold, cervical range of motion, and scapular upward rotation following a two-week intervention.
Eligible participants will be recruited through purposive sampling. Upper trapezius trigger points will be assessed by manual palpation to identify a taut band and hypersensitive nodule, followed by pressure to determine reproduction of the participant's familiar pain. Baseline assessments will include pain pressure threshold, cervical range of motion, and scapular upward rotation. After baseline assessment, 42 participants will be allocated randomly into respective groups, each having 21 participants.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Procedure: Ischemic release
Procedure: Sustained pressure Direct Myofascial release
Participants will receive a two-week physiotherapy program with three sessions per week. Each session will include heat application followed active ROM and passive stretching. Participants in Group A will receive ischemic compression in addition to standard physiotherapy. Pressure should be applied via thumb for 20 second - 1 minute until pain decreases or muscle begin to relax.
Also known as: Ischemic compression
Participants will receive a two-week physiotherapy program with three sessions per week. Each session will include heat application followed active ROM and passive stretching. Participants in Group B will receive sustained pressure direct MFR in addition to standard physiotherapy. Apply pressure to the trigger point for 8-20 seconds, maintaining it until a physical "discharge" or release is felt, which may take five minutes or more.
Pain Pressure Threshold
Pain pressure threshold will be measured using a Wagner digital pressure algometer, apply perpendicular to the identified upper trapezius trigger point with gradually increasing pressure. The pressure at which the participant first perceived pain was recorded as the pain pressure threshold (PPT) in kg/cm².
Time frame: Baseline and after 2 weeks.
Cervical range of motion
Cervical ROM will be assessed using a goniometer.
Time frame: Baseline and after 2 weeks
Scapular upward rotation
Scapular upward rotation will be assessed using a bubble inclinometer.
Time frame: Baseline and after 2 weeks
Started Sep 2026 (actual). Primary completion is estimated for Dec 2026, 3 months after the start.
Of 202 non-industry interventional studies with no phase under Myofascial Pain Syndromes, half reached primary completion within 5 months of starting (the median), counting those still running; a quarter within 2 and three quarters within 12. This study's planned 3 months is below that.
Counting every sponsor, half of 204 studies reached it within 5 months; a quarter within 2 and three quarters within 13.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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Foundation University Islamabad →