An interventional study of Speech and non-speech tasks in Stuttering, Stuttering, Childhood and Stuttering, Adult, sponsored by University of Michigan. Completed at 2 sites in United States. Open to participants aged 6 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-16.
Sponsored by University of Michigan · Not applicable, Interventional, and Basic science
This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech. Eligible participants enrolled will complete a variety of computer and speech-based tasks on up to 2 visits.
The study team will update the record to include the secondary identification number once the NIH has released the funds.
74 studies on the registry are indexed under Stuttering; 23 are open to participants now.
This study's enrollment of 145 is above the median of 44 across 57 interventional studies indexed under Stuttering.
Browse Stuttering studies →University of Michigan is the lead sponsor of 1,506 studies on the registry; 192 are open to participants now.
Of its 169 completed or terminated interventional studies of FDA-regulated products, 133 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria (adults who do not stutter):
Exclusion criteria: (adults who do not stutter)
Inclusion criteria: (adults who stutter)
Exclusion criteria: (adults who stutter)
Inclusion criteria: (children who do not stutter)
Exclusion criteria: (children who do not stutter)
Inclusion criteria: (children who stutter)
Exclusion criteria: (children who stutter)
Participants will have 2 visits.
Behavioral: Speech and non-speech tasks
Participants will have 2 visits.
Behavioral: Speech and non-speech tasks
Participants will have 1 visit.
Behavioral: Speech and non-speech tasks
Participants will have 1 visit.
Behavioral: Speech and non-speech tasks
Participants will complete speech tasks such as listening to and/or producing speech and non-speech sounds.
Phase Locking Value (PLV) - Session 1 Speech Tasks
Participants will hear a series of single syllables spoken rhythmically and will be instructed to whisper the syllable "tah" repeatedly while the recording is playing. The degree of synchronization (how well the participant's whispered syllables match the cadence of the recorded syllables they are listening to) will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals, where 0 is a complete mis-match and a 1 is a perfect match. Adults were not instructed to attempt to match the cadence (Implicit task). Child participants were instructed to attempt to match the cadence (Explicit task).
Time frame: Session 1 (up to 4 hours)
Phase Locking Value (PLV) - Session 2 Speech Tasks
Adult participants will hear a series of single syllables spoken rhythmically and will be instructed to whisper the syllable "tah" repeatedly while the recording is playing. Child participants did not attend Session 2. The degree of synchronization (how well the participant's whispered syllables match the cadence of the recorded syllables they are listening to) will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals, where 0 is a complete mis-match and a 1 is a perfect match. Adults completed this task twice. For the first test, they were not instructed to attempt to match the cadence (Implicit task). For the second test, they were instructed to attempt to match the cadence (Explicit task).
Time frame: Session 2 (up to 4 hours)
R Statistic (Resultant Vector Length)
In tapping synchronization (sensorimotor synchronization) research, the R statistic generally refers to the resultant vector length derived from circular statistics, used to quantify the consistency and stability of a participant's tapping relative to a rhythmic stimulus. It ranges from 0 to 1. 0=Complete inconsistency (taps are uniformly distributed). 1=Perfect consistency (all taps occur at the exact same relative phase).
Time frame: Session 1 (up to 4 hours)
| Milestone | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter (CWS) | Healthy Children |
|---|---|---|---|---|
| Started | 55 | 67 | 13 | 10 |
| Completed | 45 | 53 | 13 | 10 |
| Not completed | 10 | 14 | 0 | 0 |
| Withdrew: Lost to follow-up | 5 | 8 | 0 | 0 |
| Withdrew: Determined to be ineligible | 5 | 6 | 0 | 0 |
| Milestone | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter (CWS) | Healthy Children |
|---|---|---|---|---|
| Started | 45 | 53 | 0 | 0 |
| Completed | 43 | 53 | 0 | 0 |
| Not completed | 2 | 0 | 0 | 0 |
| Withdrew: Lost to follow-up | 2 | 0 | 0 | 0 |
Participants will hear a series of single syllables spoken rhythmically and will be instructed to whisper the syllable "tah" repeatedly while the recording is playing. The degree of synchronization (how well the participant's whispered syllables match the cadence of the recorded syllables they are listening to) will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals, where 0 is a complete mis-match and a 1 is a perfect match. Adults were not instructed to attempt to match the cadence (Implicit task). Child participants were instructed to attempt to match the cadence (Explicit task).
| PLV | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter (CWS) | Healthy Children |
|---|---|---|---|---|
| Implicit | 0.42 ± 0.15 | 0.42 ± 0.14 | — | — |
| Explicit | — | — | 0.42 ± 0.15 | 0.44 ± 0.21 |
Adult participants will hear a series of single syllables spoken rhythmically and will be instructed to whisper the syllable "tah" repeatedly while the recording is playing. Child participants did not attend Session 2. The degree of synchronization (how well the participant's whispered syllables match the cadence of the recorded syllables they are listening to) will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals, where 0 is a complete mis-match and a 1 is a perfect match. Adults completed this task twice. For the first test, they were not instructed to attempt to match the cadence (Implicit task). For the second test, they were instructed to attempt to match the cadence (Explicit task).
| PLV | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter (CWS) | Healthy Children |
|---|---|---|---|---|
| Implicit | 0.43 ± 0.15 | 0.42 ± 0.16 | — | — |
| Explicit | 0.56 ± 0.22 | 0.57 ± 0.24 | — | — |
In tapping synchronization (sensorimotor synchronization) research, the R statistic generally refers to the resultant vector length derived from circular statistics, used to quantify the consistency and stability of a participant's tapping relative to a rhythmic stimulus. It ranges from 0 to 1. 0=Complete inconsistency (taps are uniformly distributed). 1=Perfect consistency (all taps occur at the exact same relative phase).
| R | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter (CWS) | Healthy Children |
|---|---|---|---|---|
| R Statistic (Resultant Vector Length) | 0.91 ± 0.1 | 0.91 ± .08 | .08 ± .02 | .07 ± .004 |
Collected over From enrollment to study completion, up to two weeks.. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Adults Who Stutter (AWS) | 0/55 (0%) | 0/55 (0%) | 0/55 (0%) |
| Healthy Adults | 0/67 (0%) | 0/67 (0%) | 0/67 (0%) |
| Children Who Stutter (CWS) | 0/13 (0%) | 0/13 (0%) | 0/13 (0%) |
| Healthy Children | 0/10 (0%) | 0/10 (0%) | 0/10 (0%) |
| Age, Continuous(Years) | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter | Healthy Children | Total |
|---|---|---|---|---|---|
| Mean | 32.1 ± 11.2 | 30.7 ± 10.3 | 9.2 ± 1.2 | 10.9 ± 1.7 | 20.7 ± 6.1 |
| Sex/Gender, Customized(Participants) | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter | Healthy Children | Total |
|---|---|---|---|---|---|
| Male | 39 | 40 | 9 | 7 | 95 |
| Female | 16 | 27 | 4 | 3 | 50 |
| Race (NIH/OMB)(Participants) | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter | Healthy Children | Total |
|---|---|---|---|---|---|
| American Indian or Alaska Native | 0 | 1 | 0 | 0 | 1 |
| Asian | 13 | 9 | 0 | 0 | 22 |
| Native Hawaiian or Other Pacific Islander | 0 | 0 | 0 | 0 | 0 |
| Black or African American | 6 | 7 | 2 | 0 | 15 |
| White | 32 | 48 | 9 | 10 | 99 |
| More than one race | 4 | 2 | 2 | 0 | 8 |
| Unknown or Not Reported | 0 | 0 | 0 | 0 | 0 |
| Ethnicity (NIH/OMB)(Participants) | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter | Healthy Children | Total |
|---|---|---|---|---|---|
| Hispanic or Latino | 2 | 7 | 0 | 2 | 11 |
| Not Hispanic or Latino | 53 | 60 | 13 | 8 | 134 |
| Unknown or Not Reported | 0 | 0 | 0 | 0 | 0 |
| Region of Enrollment(participants) | Adults Who Stutter (AWS) | Healthy Adults | Children Who Stutter | Healthy Children | Total |
|---|---|---|---|---|---|
| United States | 55 | 67 | 13 | 10 | 145 |
PDFs hosted by the registry, ClinicalTrials.gov.
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