CClinicalTrials.gg
Status unknownNCT04903743Updated May 27, 2021

POPLITEAL SCIATIC NERVE BLOCK FOR DIABETIC FOOT SURGERIES

An interventional study of bupivacaine and magnesium sulfate in Diabetic Patient, sponsored by Alexandria University. Status unknown at 1 site in Egypt. Open to participants aged 40 Years to 70 Years. Per ClinicalTrials.gov, last updated 2021-05-27.

Sponsored by Alexandria University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified May 2021), so the status shown — last known as Active, not recruiting — may be out of date.

From the registry’s dates

  • Registered 4 months after the study started (first participant enrolled Jan 2021, registered May 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
40 Years to 70 Years
Sex
All
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Study summary

Popliteal Sciatic nerve block is a regional technique that provides safe and reliable perioperative anesthesia and analgesia of lower leg and foot used in diabetic patients. Different additives have been used with local anaesthetics to achieve dense and prolonged block. Magnesium sulfate possesses analgesic properties owing to its effect on NMDA receptors.

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Conditions studied

  • Diabetic Patient

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03

In context

Diabetic Foot

1,054 studies on the registry are indexed under Diabetic Foot; 222 are open to participants now.

This study's planned enrollment of 50 is below the median of 60 across 826 interventional studies indexed under Diabetic Foot.

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Lead sponsor

Alexandria University is the lead sponsor of 569 studies on the registry; 125 are open to participants now.

Of its 12 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
40 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • (ASA) II or III
  • scheduled for diabetic foot surgeries.

Exclusion criteria

Exclusion Criteria:

  • Patients who refused the anaesthetic technique,
  • whose BMI ≥ 35 kg/ m2,
  • unable to properly describe postoperative pain to investigator (dementia, delirium, psychiatric and neurological disorders),
  • patients with coagulopathy, skin infection at the site of injection,
  • preoperative use of opioid or non-steroidal anti-inflammatory drugs,
  • allergy or contraindication to studied medication
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
50 participants (estimated)

Study arms

  • Placebo comparator
    group B

    28ml of 0.25% bupivacaine and 2ml normal saline

    Drug: bupivacaine

  • Active comparator
    group BM

    received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.

    Drug: bupivacaine · Drug: magnesium sulfate

Interventions

  • Drugbupivacaine

    group B received 28ml of 0.25% bupivacaine and 2ml normal saline

  • Drugmagnesium sulfate

    group BM received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.

06

What researchers measure

Primary outcomes

  1. duration of postoperative analgesia

    evaluate the effects of adding magnesium sulfate to bupivacaine versus bupivacaine alone in popliteal sciatic nerve block with ultrasound guidance for diabetic foot surgeries as regards the duration of postoperative analgesia

    Time frame: 24 hours

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Study locations

1 site
  • rehab Abd Elaziz
    Alexandria, 000000, Egypt
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 27, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04903743
Lead sponsor
Alexandria University
Responsible party
rehab zayed (Assisstant Professor of Anesthesia, Alexandria University) — Principal investigator
First posted
May 26, 2021
Start date
Jan 10, 2021
Primary completion
Jun 20, 2021 (estimated)
Completion
Jul 10, 2021 (estimated)
Last update
May 27, 2021

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2021. You cannot join it, but the record below documents what was studied.

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