An interventional study of Aspiration of haemarthrosis and high definition MRI in ACL Injury, sponsored by Cambridge University Hospitals NHS Foundation Trust. Status unknown at 1 site in United Kingdom. Open to participants aged 18 Years to 30 Years. Per ClinicalTrials.gov, last updated 2021-05-26.
Sponsored by Cambridge University Hospitals NHS Foundation Trust · Not applicable, Interventional, and Diagnostic
The aim of this pilot study is to understand the biological changes that occur within the knee joint following injury to the anterior cruciate ligament (ACL). This will be achieved through aspiration and analysis of the haemarthrosis which fills the knee following injury. The study will look at inflammatory and healing responses using DNA, RNA and protein analysis.
This, combined with high resolution imaging of the knee and surrounding soft tissue structures, may enable a more patient specific approach to treatment of ACL injury.
5,056 studies on the registry are indexed under Wounds and Injuries; 861 are open to participants now.
This study's planned enrollment of 5 is below the median of 52 across 3,239 interventional studies indexed under Wounds and Injuries.
Browse Wounds and Injuries studies →Cambridge University Hospitals NHS Foundation Trust is the lead sponsor of 167 studies on the registry; 37 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Aspiration of haemarthrosis and high definition MRI
Pattern of injury on High Definition MRI measured by comparison with 3t MRI images
Outcome will illustrate any additional benefit of high definition MRI
Time frame: Last visit, usually 28 days
Identification of acute inflammatory mediators measured by NanoString molecular analysis
Time frame: Last visit, usually 28 days
This study is status unknown, as verified in May 2021. You cannot join it, but the record below documents what was studied.
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Cambridge University Hospitals NHS Foundation Trust