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RecruitingNCT07850544Updated Oct 7, 2026

Optimize Pattern Recognition Control of Powered Upper Limb Prosthesis

An interventional study of Condition A: Electrode Configuration and Condition B: Electrode Configuration in Prosthesis User, Prosthesis and Prosthetic, sponsored by Liberating Technologies, Inc.. Recruiting at 2 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-07.

Sponsored by Liberating Technologies, Inc. · Not applicable, Interventional, and Basic science

From the registry’s dates

  • Registered 9 months after the study started (first participant enrolled Dec 2025, registered Sep 2026).
  • Started Dec 2025; still recruiting 10 months later.
Updated Oct 7, 2026Primary outcomes revisedNewly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
32
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study is focused on optimizing methods for controlling upper-limb myoelectric prosthetic arms. If you are enrolled in this study you would be expected to visit one of the research sites for approximately 5 in-lab visits lasting about 4 hours. These visits are expected to happen within a 5-week period but may take longer depending on scheduling availability. During these visits you will be completing basic tasks similar to your everyday actions using a prosthetic arm that is provided for you.

02

Conditions studied

  • Prosthesis User
  • Prosthesis
  • Prosthetic
  • Upper Limb Amputation
  • Upper Limb Amputation Below Elbow
  • Upper Limb Amputation Below Elbow (Injury)

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03

In context

Wounds and Injuries

5,056 studies on the registry are indexed under Wounds and Injuries; 861 are open to participants now.

This study's planned enrollment of 32 is below the median of 52 across 3,239 interventional studies indexed under Wounds and Injuries.

Browse Wounds and Injuries studies →

Lead sponsor

Liberating Technologies, Inc. is the lead sponsor of 15 studies on the registry; 4 are open to participants now.

Of its 7 completed or terminated interventional studies of FDA-regulated products, 5 (71%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Aged 18 years or older
  • Unilateral transradial level limb difference
  • Current or past user of myo-electric controlled prostheses
  • Six months or more post-amputation
  • Have adequate limb length such that a wrist rotation device can fit in the check socket
  • Have adequate limb length and diameter such that at least 9 channels of electrodes fit without cross pairing
  • Well-fitting socket as determined by a Socket-Comfort Score of 6 or above
  • Capable of wearing and operating a prosthesis with a wrist rotator and multi-articulating hand
  • Capable of understanding and following multi-step instructions and completing the tasks as described
  • English speaking

Exclusion criteria

Exclusion Criteria:

  • Significant new injury that would prevent use of a prosthesis: The ability to consistently wear a prosthesis and perform activities of daily living and specific performance tasks is necessary to evaluate the relative benefits of the interventions.
  • Cognitive impairment that would adversely affect understanding of or compliance with study requirements, ability to communicate experiences, or ability to give informed consent: The ability to understand and comply with requirements of the study is essential for the study to generate useable, reliable data. The ability to obtain relevant user feedback through questionnaires and informal discussion adds significant value to this study.
  • Significant other comorbidity: Any other medical issues or injuries that would preclude completion of the study, use of the prostheses, or that would otherwise prevent acquisition of useable data by researchers.
  • Pregnant participants as risk to pregnant individuals, embryos, or fetuses are not understood.
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
32 participants (estimated)

Study arms

  • Experimental
    Sequence 1

    Each arm will test all 4 conditions but in a different order from each other.

    Device: Condition A: Electrode Configuration · Device: Condition B: Electrode Configuration · Device: Condition C: Electrode Configuration · Device: Condition D: Electrode Configuration

  • Experimental
    Sequence 2

    Each arm will test all 4 conditions but in a different order from each other.

    Device: Condition A: Electrode Configuration · Device: Condition B: Electrode Configuration · Device: Condition C: Electrode Configuration · Device: Condition D: Electrode Configuration

  • Experimental
    Sequence 3

    Each arm will test all 4 conditions but in a different order from each other.

    Device: Condition A: Electrode Configuration · Device: Condition B: Electrode Configuration · Device: Condition C: Electrode Configuration · Device: Condition D: Electrode Configuration

  • Experimental
    Sequence 4

    Each arm will test all 4 conditions but in a different order from each other.

    Device: Condition A: Electrode Configuration · Device: Condition B: Electrode Configuration · Device: Condition C: Electrode Configuration · Device: Condition D: Electrode Configuration

Interventions

  • DeviceCondition A: Electrode Configuration

    Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

  • DeviceCondition B: Electrode Configuration

    Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

  • DeviceCondition C: Electrode Configuration

    Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

  • DeviceCondition D: Electrode Configuration

    Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

06

What researchers measure

Primary outcomes

  1. ACMC

    The participant will complete a daily task (such as packing a suitcase) using their prosthetic arm. A study occupational therapist will score the participants ability along different metrics.

    Time frame: Through study completion, an average of 1 month, 1 time at each 4 site visits.

07

Study locations

2 of 2 sites recruiting
  • Shirley Ryan AbilityLab
    Chicago, Illinois 60611, United States
    Recruiting
  • Liberating Technologies, Inc. (LTI)
    Holliston, Massachusetts 01746, United States
    Recruiting
08

References and documents

Individual participant data

Plan to share: Yes — Deidentified outcomes results for participants such as ACMC, clothespin relocation task, and virtual EMG measures.

No publications or documents are linked to this record.

09

Updates

2 registry updates since Sep 25, 2026
Also revised
primary outcomes
Registered
First appeared on the registry
Sep 30, 2026
Show all 2 updates
  1. Oct 7, 2026
    Primary outcomes Revised (1 change)
    + 1 other change: verification date
  2. Sep 30, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07850544
Lead sponsor
Liberating Technologies, Inc.
Collaborators
Shirley Ryan AbilityLab, University of Hartford
Responsible party
Sponsor
First posted
Sep 30, 2026
Start date
Dec 5, 2025
Primary completion
Jun 2027 (estimated)
Completion
Jun 2027 (estimated)
Last update
Oct 7, 2026

Study contacts

Craig M Kelly
Contact
craig.kelly@liberatingtech.com
508-893-6363
Todd Farrell, PhD
principal investigator · Liberating Technologies, Inc.

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

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