An observational study in Chronic Kidney Diseases, End Stage Renal Disease on Dialysis and Frailty, sponsored by Cambridge University Hospitals NHS Foundation Trust. Status unknown at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-04-27.
Sponsored by Cambridge University Hospitals NHS Foundation Trust · Observational
The kidneys are important at getting rid of toxins and excess water from the body. If they fail, then toxins and excess water builds up within the body. Kidney failure is treated by either giving patients a new kidney (a transplant) or by removing the toxins and fluid from the body by the process of dialysis.
The investigators' aim is to personalise the care given to patients with kidney failure, and as such, they have started measuring the fitness of patients with kidney failure, who either already require dialysis or may need dialysis in the near future. This is currently done in a number of ways including measuring how strong their grip is, assessing their walking speed and asking questions about how difficult they find certain activities.
In the future, the investigators think that this will allow targeted treatments to help improve their fitness and potentially identify any problems earlier.
Current approaches to measuring activity and fitness have limitations and in particular may over- or underestimate the level of the physical activity. To over come these limitations, participants will be asked to wear an activity tracker (called an accelerometer) on for a week. Readings from the accelerometer will be compared against the other markers of fitness and activity to see if they are comparable. It will also be noted whether patients are prepared to wear the device for 7 days (compliance).
3,840 studies on the registry are indexed under Kidney Diseases; 500 are open to participants now.
This study's planned enrollment of 40 is below the median of 192 across 1,033 observational studies indexed under Kidney Diseases.
Browse Kidney Diseases studies →Cambridge University Hospitals NHS Foundation Trust is the lead sponsor of 167 studies on the registry; 37 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Low clearance pre-dialysis patients referred to the Low Clearance Clinic and / or who have commenced on haemodialysis
Exclusion Criteria:
Wearing accelerometer (fitness tracker) for 7 days.
Device: GeneActiv wrist worn accelerometer
Wearing accelerometer (fitness tracker) for 7 days.
Device: GeneActiv wrist worn accelerometer
Wrist worn device worn for 7 days
Acceptability
The acceptability of physical activity measures in frailty assessment in patients from the low clearance and dialysis clinic as determined by the percentage of time, device worn during the 7-day period.
Time frame: 7 days
Measurement of physical activity by the accelerometer
Measurement of physical activity by the accelerometer (no units)
Time frame: 7 days
Fried Frailty Phenotype (no units)
Fried Frailty Phenotype (no units)
Time frame: 1 day
Grip strength (in kilograms)
Grip strength (in kilograms)
Time frame: 1 day
Walking speed (in seconds measured over 15 feet)
Walking speed (in seconds measured over 15 feet)
Time frame: 1 day
Clinical Frailty Scale (no units)
Clinical Frailty Scale (no units)
Time frame: 1 day
10 Point Cognitive Screener (no units)
10 Point Cognitive Screener (no units)
Time frame: 1 day
4AT Assessment Tool of Cognitive Impairment (no units)
4AT Assessment Tool of Cognitive Impairment (no units)
Time frame: 1 day
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.
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Cambridge University Hospitals NHS Foundation Trust