An observational study in End Stage Kidney Disease, sponsored by Hacettepe University. Status unknown. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-12-16.
Sponsored by Hacettepe University · Observational
Many systems such as the cardiovascular, pulmonary, musculoskeletal, hematological, immunological, gastrointestinal, central nervous system are affected due to decreased kidney function. The aim of this study was to investigate the relationship between physical performance and sarcopenia, peripheral muscle strength, activities of daily living, cognitive functions, physical activity level, fragility, pain in hemodialysis patients.
A high prevalence of sarcopenia has been reported in end stage kidney disease. The incidence of sarcopenia increases with age. Muscle atrophy is caused by an imbalance between the anabolic and catabolic processes in chronic kidney disease. Sarcopenia and physical inactivity progress synergistically. Decreased physical performance is associated with sarcopenia. In hemodialysis patients, daily physical activity level and physical performance decrease. Cognitive impairment is common in chronic kidney disease. Uremic toxins can cause a decrease in cognitive function. One of the most important problems associated with hemodialysis is pain and pain negatively affects functional capacity and quality of life.
1,208 studies on the registry are indexed under Sarcopenia; 402 are open to participants now.
This study's planned enrollment of 26 is below the median of 120 across 419 observational studies indexed under Sarcopenia.
Browse Sarcopenia studies →Hacettepe University is the lead sponsor of 983 studies on the registry; 212 are open to participants now.
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Patients aged 18 years and older, who are diagnosed with end stage kidney disease at the Hacettepe University, Faculty of Medicine, Department of Internal Diseases, Nephrology Subdivision
Exclusion Criteria:
Sarcopenia
Sarcopenia will be evaluated using SARC-F questionnaire. For SARC-F, a total score of ≥ 4 indicates sarcopenia.
Time frame: 5 minutes
Physical performance will be evaluated using Short physical performance battery.
The total score of Short physical performance battery ranges from 0 to 12.
Time frame: 10 minutes
Physical performance will be evaluated using 1 minute sit to stand test.
1 minute sit to stand test, the maximum number of repetitions within the established time was recorded
Time frame: 5 minutes
Pain level
Pain will be evaluated using Short-form McGill Pain questionnaire
Time frame: 5 minutes
Peripheral muscle strength
Knee extensor and hand grip strength will be evaluated using dynamometer.
Time frame: 5 minutes
Cognitive function
Cognitive function will be evaluated using Standardized Mini-Mental State Examination. The test is a 30-point screening tool. Higher scores mean a better outcome.
Time frame: 10 minutes
Physical activity level
Physical activity level will be evaluated using International Physical Activity Questionnaire-Short Form
Time frame: 5 minutes
Fragility
Fragility will be evaluated using the five Fried frailty criteria (unintentional weight loss, exhaustion, weakness, slowness, low physical activity). The total score is interpreted as follows: 0 non-frail, 1-2 pre-frail and 3-5 frail
Time frame: 5 minutes
Activities of daily living
Activities of daily living will be evaluated using Barthel Index for Activities of Daily Living.The total score is100 and higher scores mean a better outcome.
Time frame: 10 minutes
No study locations are listed for this record.
This study is status unknown, as verified in Dec 2020. You cannot join it, but the record below documents what was studied.
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Hacettepe University