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CompletedNCT04613843Updated Jul 26, 2022

Cold Water Immersion Stirring in Hyperthermic Individuals

An interventional study of Water Stirring and No Water Stirring in Hyperthermia, sponsored by State University of New York at Buffalo. Completed at 1 site in United States. Open to participants aged 18 Years to 39 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-07-26.

Sponsored by State University of New York at Buffalo · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year after the study started (first participant enrolled Oct 2019, registered Oct 2020).
Phase
Not applicable
Study type
Interventional
Enrollment
16
Allocation
Randomized
Ages
18 Years to 39 Years
Sex
All
01

Study summary

The best way to cool a very hot person is using cold water immersion, however, the optimization of this technique has not been established. The goal of this study is to determine differences in cooling rates among two types of cold water immersion and passive cooling following immersion.

02

Conditions studied

  • Hyperthermia

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03

In context

Hyperthermia

481 studies on the registry are indexed under Hyperthermia; 92 are open to participants now.

This study's enrollment of 16 is below the median of 60 across 368 interventional studies indexed under Hyperthermia.

Browse Hyperthermia studies →

Lead sponsor

State University of New York at Buffalo is the lead sponsor of 294 studies on the registry; 65 are open to participants now.

Of its 19 completed or terminated interventional studies of FDA-regulated products, 15 (79%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 39 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 18-39 y old men and women
  • Self-reported to be healthy
  • Currently completes aerobic exercise at least 30 minutes a day, at least 2 days per week

Exclusion criteria

Exclusion Criteria:

  • History of any cardiovascular, neurologic, renal, or metabolic disease
  • History of any contraindications on the CoreTemp contraindications and warnings document
  • Current tobacco use or regular use within the last 2 years
  • Taking medications with known thermoregulatory or cardiovascular effects (e.g., aspirin, beta blockers, diuretics, psychotropics, etc.)
  • History of exertional heat stroke
  • Currently pregnant or breastfeeding
  • Inability to follow the rules of the protocols or understand the consent form
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
16 participants (actual)

Study arms

  • Active comparator
    Water stirring

    Other: Water Stirring

  • Experimental
    No water stirring

    Other: No Water Stirring

Interventions

  • OtherWater Stirring

    Following an active heating protocol, the cooling intervention includes vigorous water stirring throughout cold water immersion.

  • OtherNo Water Stirring

    Following an active heating protocol, the cooling intervention includes no water stirring throughout cold water immersion.

06

What researchers measure

Primary outcomes

  1. Cooling rate

    The core temperature cooling rate

    Time frame: 20 minutes

07

Study locations

1 site
  • Center for Research and Exercise in Special Environments
    Buffalo, New York 14214, United States
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will be made available upon written request.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 26, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04613843
Responsible party
Riana Pryor (Principal Investigator, State University of New York at Buffalo) — Principal investigator
First posted
Nov 3, 2020
Start date
Oct 23, 2019
Primary completion
May 1, 2022
Completion
May 1, 2022
Last update
Jul 26, 2022

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2022. You cannot join it, but the record below documents what was studied.

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