An observational study in Complex Regional Pain Syndromes and Chronic Pain, sponsored by Uppsala University. Completed at 1 site in Sweden. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2024-02-28.
Sponsored by Uppsala University · Observational
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Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features. The diagnosis is subdivided in CRPS type 1 where no nerve injury has been identified, and CRPS type 2 when a major nerve injury has been verified.
A combination of exposure in vivo, a form of behaviour therapy where the patient is gradually confronted with avoided movements and activities, and interventions directly targeting a hypothesized cortical reorganisation is an interesting novel approach for treating CRPS.
The present study consists of (1) a qualitative interview study with 10-15 subjects that has received this form of treatment, in order to better understand their experience and effects of the treatment, and (2) a case series with long-term follow-up of 3-5 subjects that received the treatment för 5-8 years ago, in order to study the long term effects of the treatment.
206 studies on the registry are indexed under Complex Regional Pain Syndromes; 54 are open to participants now.
This study's enrollment of 10 is below the median of 58 across 44 observational studies indexed under Complex Regional Pain Syndromes.
Browse Complex Regional Pain Syndromes studies →Uppsala University is the lead sponsor of 390 studies on the registry; 86 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Subjects with CRPS 1 or 2, diagnosed according to the Budapest criteria that has received in-patient treatment at Uppsala University Hospital, comprised of graded exposure therapy in vivo, in combination with methods targeting cortical reorganisation.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Behavioral: Multimodal rehabilitation
A combination of exposure in vivo and interventions directly targeting the cortical reorganization for treating CRPS.
Diagnosis
Whether the subject still fulfill diagnostic criteria for CRPS
Time frame: 1 day
Subjective experience
A qualitative interview targeting the subjects own experience of the treatment and its effect
Time frame: 1 day
Level of pain
Subjective level of pain on a Likert-scale 0-10 (NRS)
Time frame: 1 day
Subjective experience of quality of life
Quality of life, measured with the RAND-36 (0-100, higher scores mean a better outcome)
Time frame: 1 day
Global impression of change
Global impression of change measured with a single question (0-6, higher scores mean a better outcome)
Time frame: 1 day
Acceptance of pain
Measured with the Chronic Pain Acceptance Questionnaire, CPAQ (0-156, higher scores mean a better outcome)
Time frame: 1 day (0-156, higher scores mean a better outcome)
Fear of pain
Measured with the Tampa Scale of Kinesiophobia, TSK (0-52, lower scores mean a better outcome)
Time frame: 1 day (0-52, lower scores mean a better outcome)
Pain catastrophizing
Measured with Pain Catastrophizing Scale, PCS (0-52, lower scores mean a better outcome)
Time frame: 1 day (0-52, lower scores mean a better outcome)
Avoidance of activities
Measured with the Photograph Series of Daily Activities, PHODA (0-100, lower scores mean a better outcome)
Time frame: 1 day (0-100, lower scores mean a better outcome)
Neglect of the affected limb
Measured with a five item questionnaire (0-36, lower scores mean a better outcome)
Time frame: 1 day (0-36, lower scores mean a better outcome)
Subjective experience of quality of life 2
EuroQol 5D, EQ-5D (0-15, higher scores means a better outcome)
Time frame: 1 day
Subjective experience of quality of life 3
Life Satisfaction Questionnaire, LiSat 11 (11-66, higher scores means a better outcome)
Time frame: 1 day
Plan to share: Undecided
No publications or documents are linked to this record.
Ran from Sep 2020 to primary completion in Jun 2021, 9 months.
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This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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