An interventional study of Single Palatal TAD and Two buccal TADs in Anterior Openbite, sponsored by University of Dundee. Active, not recruiting at 1 site in United Kingdom. Open to participants aged 12 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-04-20.
Sponsored by University of Dundee · Not applicable, Interventional, and Treatment
Participants are orthodontic patients with anterior open bite (AOB) malocclusion. These patients will be treated by molar intrusion achieved using one of two interventions, either orthodontic fixed appliances incorporating a single palatal Temporary Anchorage Device (TAD) or orthodontic fixed appliances incorporating two buccal TADs
Participants will be recruited from those attending Dundee Dental Hospital Orthodontic Department and those currently awaiting treatment. Those that meet the inclusion and exclusion criteria will be invited to participate. After obtaining consent they will be allocated to receive one of the two interventions. The two interventions represent the currently available options for treatment of mild - moderate (1-6mm) anterior open bite in the Orthodontic Department and as such patients will be receiving routine treatment regardless of the arm they are randomised to. In order to assess the more effective intervention additional records will be taken during the treatment involving additional cephalometric radiographs, additional intra-oral scans or dental impressions (See later for details). Primary outcome is at the end of intrusion with TADs after 9-12 months, but participants will be followed until completion of treatment for the secondary outcome of stability of intrusion and overbite correction
34 studies on the registry are indexed under Open Bite; 8 are open to participants now.
This study's planned enrollment of 32 is close to the median of 30 across 28 interventional studies indexed under Open Bite.
Browse Open Bite studies →University of Dundee is the lead sponsor of 113 studies on the registry; 3 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 3 (60%) have results posted.
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Exclusion Criteria:
Single Palatal TAD for orthodontic molar intrusion
Device: Single Palatal TAD
Two buccal TADs for orthodontic molar intrusion
Device: Two buccal TADs
A single mini-screw inserted in the mid-palate
Two buccal TADs inserted in the upper jaw
Molar intrusion
Amount of upper molar intrusion measured in mms on cephalometric radiograph
Time frame: 9-12 months after treatment commences
Overbite (vertical overlap of anterior teeth)
Change in overbite (vertical overlap of anterior teeth) measured clinically directly from the teeth with a ruler and on 3D dental scans using 3D analysis software, both in mms
Time frame: 9-12 months after treatment commences
Patient Experience
Patient experience with the use of temporary anchorage devices for intrusion by validated questionnaire which uses 3 or 4 point Likert Scales for a range of questions across relevant doamins. Depending on the question the scales are 'Improved/Same/Worse/Much worse' or 'Not at all / A little / A lot' or 'I do more / no difference / I do less' (Yassir et al 2017)
Time frame: 9-12 months after treatment commences
Plan to share: No
This study is active, not recruiting, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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