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CompletedNCT04408404Updated May 29, 2020

Factors Influencing Perioperative Mortality in Type A Acute Aortic Dissections Operated at Dijon University Hospital

An observational study in Aortic Dissection, sponsored by Centre Hospitalier La Chartreuse. Completed at 1 site in France. Open to participants aged 18 Years to 99 Years. Per ClinicalTrials.gov, last updated 2020-05-29.

Sponsored by Centre Hospitalier La Chartreuse · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
230
Ages
18 Years to 99 Years
Sex
All
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Study summary

Type A acute aortic dissections are a rare condition whose natural evolution is catastrophic. Global mortality remains high even if it decreased last years. This is probably due to improvement of diagnostic techniques and the evolution of surgical practices. It is however important to have medical data and statistics obtained in past years in order to better understand the factors influencing peroperative mortality and thereby to continue this improvement.

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Conditions studied

  • Aortic Dissection

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In context

Aortic Dissection

386 studies on the registry are indexed under Aortic Dissection; 117 are open to participants now.

This study's enrollment of 230 is above the median of 183 across 180 observational studies indexed under Aortic Dissection.

Browse Aortic Dissection studies →

Lead sponsor

Centre Hospitalier La Chartreuse is the lead sponsor of 7 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 99 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients who underwent aortic dissection surgery in Dijon Burgundy University Hospital since the 01 January 2007 and the 31 december 2017.

Inclusion criteria

  • patients who underwent aortic dissection surgery in Dijon Burgundy University Hospital

Exclusion criteria

Exclusion Criteria:

  • patients who died before the surgical incision
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
230 participants (actual)
Patient registry
No

Groups and cohorts

  • Type A aortic dissection

    Patient operated for type A acute aortic dissection between 01 January 2007 and 31 December 2017 in Dijon Burgundy University Hospital

    Procedure: Acute aortic dissection

Interventions

  • ProcedureAcute aortic dissection

    Acute aortic dissection treatment include Bentall procedure, Tyrone David procedure, Yacoub procedure or ascendant aortic replacement with or without aortic valve replacement, ascendant aortic root remodelling (all are standard of care procedures)

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What researchers measure

Primary outcomes

  1. Monitor peri-operative mortality incidence rates

    Mortality during peri-operative acute aortic dissection procedure

    Time frame: 1 day

Secondary outcomes

  1. Monitor peri-operative morbidity incidence rates

    Stroke, Kidney failure, Reexploration for bleeding

    Time frame: 1 day

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Study locations

1 site
  • Cardiovascular and thoracic surgery Unit - Dijon University Hopital
    Dijon, 21000, France
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References and documents

Individual participant data

Plan to share: No — All patients are informed before surgery that all the medical data included in the medical record could be used in cardiovascular monocentric retrospective study. No data shared.

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 29, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04408404
Lead sponsor
Centre Hospitalier La Chartreuse
Responsible party
MORGANT Marie-Catherine (Principal investigator, Centre Hospitalier La Chartreuse) — Principal investigator
First posted
May 29, 2020
Start date
Jan 1, 2018
Primary completion
Jan 1, 2018
Completion
May 26, 2020
Last update
May 29, 2020

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2020. You cannot join it, but the record below documents what was studied.

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