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Status unknownNCT04368975Updated Apr 30, 2020

ARDS Caused by COVID-19

An observational study in Acute Respiratory Failure With Hypoxia, sponsored by Hospital Clinic of Barcelona. Status unknown at 1 site in Spain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-04-30.

Sponsored by Hospital Clinic of Barcelona · Observational

The sponsor has not verified this record recently (last verified Apr 2020), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
500
Ages
18 Years and older
Sex
All
01

Study summary

Patients with the acute respiratory distress syndrome (ARDS) have markedly varied clinical presentations. Main characteristics of mechanically ventilated ARDS caused by COVID-19, and adherence to lung-protective ventilation strategies are not well known.

Read the detailed description

This is a multicenter, prospective, observational study in consecutive, mechanically ventilated patients with ARDS caused by COVID-19 (as defined by the Berlin criteria and confirmed COVID-19 infection in a respiratory tract sample), admitted into a network of 27 Spanish and Andorran intensive care units (ICUs). Clinical features, ventilatory management, and clinical outcomes will be examined

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Conditions studied

  • Acute Respiratory Failure With Hypoxia
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In context

Respiratory Insufficiency

1,650 studies on the registry are indexed under Respiratory Insufficiency; 296 are open to participants now.

This study's planned enrollment of 500 is above the median of 100 across 545 observational studies indexed under Respiratory Insufficiency.

Browse Respiratory Insufficiency studies →

Lead sponsor

Hospital Clinic of Barcelona is the lead sponsor of 319 studies on the registry; 55 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Critically ill patients with acute respiratory failure requiring invasive mechanical ventilation

Inclusion criteria

  • aged 18 years or older
  • intubated and mechanically ventilated
  • confirmed COVID-19 infection in a respiratory tract sample
  • acute onset of ARDS, as defined by the Berlin criteria

Exclusion criteria

Exclusion Criteria:

  • patients with non-confirmed SARS-CoV-2 infection according to WHO guidance
  • patients with no information on respiratory parameters
  • non- intubated patients
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
500 participants (estimated)
Target follow-up
28 Days
Patient registry
Yes
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What researchers measure

Primary outcomes

  1. Discontinuation from mechanical ventilation

    Time frame: 28 days

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Study locations

1 of 1 sites recruiting
  • Ricard Mellado
    Barcelona, 08036, Spain
    Recruiting
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References and documents

Publications

  • Ferrando C, Suarez-Sipmann F, Mellado-Artigas R, Hernandez M, Gea A, Arruti E, Aldecoa C, Martinez-Palli G, Martinez-Gonzalez MA, Slutsky AS, Villar J; COVID-19 Spanish ICU Network. Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS. Intensive Care Med. 2020 Dec;46(12):2200-2211. doi: 10.1007/s00134-020-06192-2. Epub 2020 Jul 29. Erratum In: Intensive Care Med. 2021 Jan;47(1):144-146. doi: 10.1007/s00134-020-06251-8. PubMed 32728965 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 30, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04368975
Lead sponsor
Hospital Clinic of Barcelona
Collaborators
Ubikare
Responsible party
Carlos Ferrando Ortolá (Head of Surgical Intensive Care Unit, Hospital Clinic of Barcelona) — Principal investigator
First posted
Apr 30, 2020
Start date
Mar 12, 2020
Primary completion
Apr 21, 2020
Completion
Dec 31, 2020 (estimated)
Last update
Apr 30, 2020

Study contacts

Carlos Ferrando, PhD
Contact
cmferrando@clinic.cat
609892732
Sara Darriba, PhD
Contact
darriba@clinic.cat
Carlos Ferrando
principal investigator · Medical Research and Clinical Consulting

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Apr 2020. You cannot join it, but the record below documents what was studied.

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