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Status unknownNCT04295434BP-CONUpdated Mar 4, 2020

Blood Pressure Control in ESH Excellence Centres

An observational study in Blood Pressure, Lifestyle Risk Reduction and White Coat Hypertension, sponsored by Clinical Hospital Centre Zagreb. Status unknown at 46 sites in 22 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-03-04.

Sponsored by Clinical Hospital Centre Zagreb · Observational

The sponsor has not verified this record recently (last verified Mar 2020), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
3,000
Ages
18 Years and older
Sex
All
01

Study summary

In the BP-CON-ESH study we are going to include and analyze treated hypertensive patients seen consecutively by the ESH Excellence Centres. Blood pressure will be measured as usually done in the office, but care will be adopted to make measurements highly standardized in all Centres. The primary goals will be to determine the global, regional and country rates of hypertension control in Europe. Other goals will be to identify global and regional factors associated with blood pressure control in different European regions. The results obtained in the BP-CON-ESH project will be used to refine treatment strategies for improvement of blood pressure control and will serve as a basis for assessing future changes and trends in Europe.

Read the detailed description

The most important task of the European Society of Hypertension is to improve blood pressure treatment and increase blood pressure control, thus decreasing cardiovascular risk, premature cardiovascular and renal morbidity and mortality, with in addition a reduction of health-care costs. More than a decade ago, the European Society of Hypertension established a network of Excellence Centres. Those centres are leading institutions for the diagnosis and treatment of hypertension and thus are front runners of good clinical practice in hypertension management in their countries. An important task of the Excellence Centres is also to be active in research, particularly in projects conducted by the European Society of Hypertension. The ongoing BP-CON-ESH project on the rate of blood pressure control in hypertensive patients addresses the most elementary,but at the same timethe most important aspect in hypertension management, because the observed low rates of blood pressure control is the reason why hypertension is still today the leading cause of death worldwide.

In the BP-CON-ESH study we are going to include and analyze treated hypertensive patients seen consecutively by the ESH Excellence Centres. Blood pressure will be measured as usually done in the office, but care will be adopted to make measurements highly standardized in all Centres.

The primary goals will be to determine the global, regional and country rates of hypertension control in Europe. Other goals will be to identify global and regional factors associated with blood pressure control in different European regions. It is well known that the overall control of hypertension in Europe is still insufficient. However, the problem is not the same across Europe. Differences in healthcare systems exist among European countries, and in some countries government healthcare system only partially reimburse costs of antihypertensive therapy. There are also differences in gross national product, educational levels, salt consumption, prevalence of obesity and other aspects. These could cause dissimilarities in hypertension prevalence, achieved blood pressure control and cardiovascular mortality among European regions.

The results obtained in the BP-CON-ESH project will be used to refine treatment strategies for improvement of blood pressure control and will serve as a basis for assessing future changes and trends in Europe.

02

Conditions studied

  • Blood Pressure
  • Lifestyle Risk Reduction
  • White Coat Hypertension

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Keywords

  • Blood pressure
  • Hypertension
  • Control
  • European
  • Excellence centres
03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

This study's planned enrollment of 3,000 is above the median of 210 across 1,359 observational studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Clinical Hospital Centre Zagreb is the lead sponsor of 31 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients with hypertension that are under supervision of excellence centres participating in the study.

Inclusion criteria

  • Signed informed consent

Exclusion criteria

Exclusion Criteria:

  • Pregnancy and breastfeeding
  • Terminal malignancy, reduced life expectancy (\<6 months)
  • Amputated limb
  • Dementia
  • Patients living in a nursing home
  • Unsigned informed consent
05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
3,000 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Blood pressure control

    Difference in blood pressure values between ESH Excellence Centres

    Time frame: Through study completion, an average of 1 year

07

Study locations

30 of 46 sites recruiting
  • Center of Preventive Cardiology, Yerevan
    Yerevan, 0014, Armenia
    Recruiting
  • Klinikum Wels-Grieskirchen
    Wels, 4600, Austria
    Recruiting
  • Erasmus Hospital
    Brussels, 1070, Belgium
    Recruiting
  • CHU de Liège
    Liège, 4000, Belgium
    Recruiting
  • Ambroise Paré University Hospital
    Mons, 7000, Belgium
    Recruiting
  • University Hospital "St. Anna"
    Sofia, 1750, Bulgaria
    Recruiting
  • University hospital centre Zagreb
    Zagreb, Grad Zagreb 10000, Croatia
    Recruiting
  • Charles University Medical School and University Hospital
    Plzen, 30599, Czechia
    Recruiting
  • Center for Hypertension, Charles University, Prague
    Praha, 12808, Czechia
    Recruiting
  • Institute for Clinical and Experimental Medicine (IKEM) and Thomayer Hospital, Prague
    Praha, 14059, Czechia
    Recruiting
  • Tallinn Hypertension Excellence Centre
    Tallinn, 13419, Estonia
    Recruiting
  • Hypertension Center Berlin Charité
    Berlin, 10117, Germany
    Recruiting
  • Hypertoniezentrum Bonn
    Bonn, 53123, Germany
    Not yet recruiting
  • Medizinische Hochschule Hannover
    Hanover, 30625, Germany
    Recruiting
  • Universitätskliniken des Saarlandes
    Homburg, D-66421, Germany
    Recruiting
  • Hypertension Center Munich
    Munich, 80333, Germany
    Recruiting
  • Hypertension and Cardiovascular Prevention Clinic, 3rd Department of Medicine, Evangelismos Hospital
    Athens, 10676, Greece
    Recruiting
  • Hypertension Clinic, University Hospital Laiko
    Athens, 11527, Greece
    Recruiting
  • University of Athens, Hippokration Hospital
    Athens, 11527, Greece
    Recruiting
  • Hypertension Clinic, Department of Cardiology, KAT General Hospital
    Athens, 14561, Greece
    Recruiting
  • Hypertension Clinic, Cardiology Department, Asklepeion Hospital
    Athens, Greece
    Recruiting
  • University Hospital of Heraklion
    Heraklion, 71110, Greece
    Recruiting
  • Hypertension Center, Department of Nephrology, University Hospital of Ioannina
    Ioánnina, 45500, Greece
    Recruiting
  • Hypertension Outpatient Clinic, 1st Propedeutic Dept. of Internal Medicine, AHEPA Hospital
    Thessaloníki, 54636, Greece
    Recruiting
  • Hypertension Center, Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki
    Thessaloníki, 54642, Greece
    Recruiting
  • Aristotle University of Thessaloniki, Papageorgiou General Hospital
    Thessaloníki, 56403, Greece
    Recruiting
  • Assuta Ashdod University Hospital
    Ashdod, 7747629, Israel
    Not yet recruiting
  • Centre of Prevention and Treatment of Arterial Hypertension and Cardiovascular Risk Factors
    Brescia, Italy
    Not yet recruiting
  • S. Luca Hospital, Istituto Auxologico Italiano
    Milan, 20149, Italy
    Recruiting
  • Ospedale Niguarda, Dip. De Gasperis e Università di Milano Bicocca
    Milan, 20162, Italy
    Recruiting
  • Napoli Hypertension Excellence Centre, Federico II Clinic Research Center for Hypertension and Related Conditions
    Napoli, 80131, Italy
    Not yet recruiting
  • Excellence Centre of Hypertension, Department of Medical Sciences, University of Torino
    Torino, 10124, Italy
    Not yet recruiting
  • American University Center, Hypertension/Vascular Medicine Division (Associated Centre)
    Beirut, Lebanon
    Not yet recruiting
  • Kaunas Hypertension Excellence Centre
    Kaunas, 47101, Lithuania
    Not yet recruiting
  • University Hospital Maastricht
    Maastricht, 6229 HX, Netherlands
    Not yet recruiting
  • Radboud University of Nijmegen Medical Center
    Nijmegen, 6525 GA, Netherlands
    Not yet recruiting
  • Department of Internal Medicine, Hypertension and Vascular Diseases, Warsaw Medical University
    Warsaw, 02-091, Poland
    Not yet recruiting
  • Centro Hospitalar do Alto Ave, Minho University
    Guimarães, Portugal
    Recruiting
  • Department of Cardiology and Internal Medicine, Emergency Clinical Hospital of Bucharest
    Bucharest, Romania
    Recruiting
  • Centre for Hypertension of the Clinical Centre of Serbia
    Belgrad, 11000, Serbia
    Recruiting
  • Hipertensión Clinic, Internal Medicine, Hospital Clinico, University of Barcelona
    Barcelona, 08036, Spain
    Not yet recruiting
  • Hypertension Clinic, Nephrology Department, Reina Sofia University Hospital
    Córdoba, 14004, Spain
    Not yet recruiting
  • Danderyd University Hospital
    Stockholm, 182 57, Sweden
    Not yet recruiting
  • National Scientific Center "The M.D. Strazhesko Institute of Cardiology"
    Kyiv, 02000, Ukraine
    Not yet recruiting
  • St. Bartholomew's Royal London School of Medicine & Dentistry
    London, E1 2AD, United Kingdom
    Not yet recruiting
  • The Pearl-Rose Clinic (Hypertension & Cardiovascular Risk), Hammersmith Hospital,
    London, W12 0HS, United Kingdom
    Not yet recruiting
08

References and documents

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 4, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04295434
Lead sponsor
Clinical Hospital Centre Zagreb
Collaborators
European Society of Hypertension
Responsible party
Prof. Bojan Jelaković (Professor, Clinical Hospital Centre Zagreb) — Principal investigator
First posted
Mar 4, 2020
Start date
Oct 1, 2018
Primary completion
Oct 1, 2020 (estimated)
Completion
Mar 1, 2021 (estimated)
Last update
Mar 4, 2020

Study contacts

Bojan Jelaković, MD, PhD
Contact
jelakovicbojan@gmail.com
00385959030751
Branimir Krtalić, MD
Contact
bkrtalic@gmail.com
00385923314348
Bojan Jelaković, MD, PhD
principal investigator · Clinical Hospital Centre Zagreb

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.

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