CClinicalTrials.gg
Status unknownNCT04275427Updated Feb 19, 2020

The Study of the Efficacy of Laser Acupuncture on Osteoarthritis Knees by Using Magnetic Resonance Imaging, Clinical Evaluation, and Movement Analysis

An interventional study of LA-400 laser acupuncture in Osteoarthritis, Knee, sponsored by Shin Kong Wu Ho-Su Memorial Hospital. Status unknown at 1 site in Taiwan. Open to participants aged 20 Years to 70 Years. Per ClinicalTrials.gov, last updated 2020-02-19.

Sponsored by Shin Kong Wu Ho-Su Memorial Hospital · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Mar 2019), so the status shown — last known as Recruiting — may be out of date.

From the registry’s dates

  • Registered 1 year 1 month after the study started (first participant enrolled Jan 2019, registered Feb 2020).
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Non-randomized
Ages
20 Years to 70 Years
Sex
All
01

Study summary

To study the efficacy of laser acupuncture on osteoarthritis (OA) knee patients by magnetic resonance imaging (MRI), clinical evaluation and movement analysis.

Read the detailed description

The Kellgren-Lawrence (KL) grading scheme for OA knee

Patient selecting flow Age: 20-70 year old Grade II-III knee OA Exlusion: Trauma history/ Space claustrophobia /Severe chronic disease/ Malignancy Pregnancy Study Cases 40 Randomize Pre-treatment MRI (to evaluate grade of OA knee/ the T2 signal of the cartilage), MRS (baseline glutamate), Movement analysis(sit to stand), Maximum strength ratio of Quadriceps/Hamstring WOMAC Post-treatment evaluation laser therapy Modality: LA-400 Treatment protocol of low level laser

  • 40mW, 50Hz, 808nm (invisible light) , 15min
  • The effect of laser acupuncture is dose dependent Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older SubjectsJ Lasers Med Sci. 2016 Spring; 7(2): 112-119
  • 830nm is an effective form of treatment for chronic knee pain caused by knee osteoarthritis. Low Level Laser Therapy for chronic knee joint pain patientsLaser Ther.

    2014 Dec 27; 23(4): 273-277

  • Duration: 2 weeks Frequency: 3 times/week
  • Control group: no treatment Acupuncture point: EX- LE-5, EX-EL 2, SP10
02

Conditions studied

  • Osteoarthritis, Knee
03

In context

Osteoarthritis

4,398 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.

This study's planned enrollment of 30 is below the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.

Browse Osteoarthritis studies →

Lead sponsor

Shin Kong Wu Ho-Su Memorial Hospital is the lead sponsor of 65 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Kellgren-Lawrence grade II \~ III

Exclusion criteria

Exclusion Criteria:

  • Trauma history/ Space claustrophobia/ Severe chronic disease/Malignancy Pregnancy
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    study laser group

    laser therapy on knee for 2 weeks

    Device: LA-400 laser acupuncture

  • No intervention
    control group

    no intervention

Interventions

  • DeviceLA-400 laser acupuncture

    low level laser

06

What researchers measure

Primary outcomes

  1. difference on MRI post- versus pre- treatment

    compare the apparent diffusion coefficient (ADC) value post- and pre- treatment, suppose that the higher the value, the less inflammation in target tissue

    Time frame: 2 weeks

Secondary outcomes

  1. Improve stability on movement analysis

    Calculate the area of center of posture (COP) during the movement. Suppose that the lower value, the higher stability.

    Time frame: 2 weeks

Other outcomes

  1. decreased WOMAC score

    The Western Ontario and McMaster Universities Osteoarthritis Index, pain(0-20), stiffness(0-8), functional limitation(0-68). The higher the score, the worse the pain, stiffness and limitation

    Time frame: 2 weeks

07

Study locations

1 of 1 sites recruiting
  • ShinKongHospital
    Taipei, 111, Taiwan
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 19, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04275427
Lead sponsor
Shin Kong Wu Ho-Su Memorial Hospital
Responsible party
Sponsor
First posted
Feb 19, 2020
Start date
Jan 1, 2019
Primary completion
Dec 1, 2020 (estimated)
Completion
Jan 1, 2021 (estimated)
Last update
Feb 19, 2020

Study contacts

Ching Wen Huang, M.D.
Contact
b318is2002@yahoo.com.tw
886-2-28332211 ext. 2147

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion