An observational study in Obesity, Diet Habit and Genetic Predisposition, sponsored by Hacettepe University. Completed at 1 site in Turkey. Open to participants aged 24 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-12-19.
Sponsored by Hacettepe University · Observational
Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.
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This study's enrollment of 400 is above the median of 135 across 1,283 observational studies indexed under Obesity.
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400 unrelated individuals, aged 24-50 years
Inclusion Criteria:
obese (BMI ≥25.00 kg/m2, n=200)
non-obese (BMI= 18.50-24.99 kg/m2, n=200)
Genetic analysis of two SNPs at FTO gene
FTO SNPs rs9939609 and rs10163409
Time frame: up to 36 weeks
Anthropometric measurements
Body mass index, waist circumference, hip circumference, body composition
Time frame: up to 36 weeks
Biochemical measurements
lipid profile, glucose, insulin, adiponectin
Time frame: up to 36 weeks
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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Hacettepe University