An observational study in Periodontal Diseases, sponsored by Aydin Adnan Menderes University. Completed at 1 site in Turkey. Open to participants aged 7 Years to 14 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-11-29.
Sponsored by Aydin Adnan Menderes University · Observational
This study aimed to evaluate the levels of interleukin 18 and tumor necrosis factor-alpha (TNF-α) in gingival crevicular fluid (GCF) of children with type 1 diabetes mellitus and gingivitis.
Eighty eight children (44 with type 1 diabetes mellitus and 44 healty; age range 7-14 years) will be recruited for the study. The children will be classified into four subgroups based on their periodontal status; 1) Children with gingivitis and diabetes mellitus (MG, n=22); 2) Children with type 1 diabetes mellitus with healthy periodontium (MH, n=22); 3)Healthy children with gingivitis (HG, n=22); 4) Healthy children with healthy periodontium (HH, n=22). Probing pocket depth (PPD), gingival index (GI) and plaque index (PI) will be recorded. Interleukin-18 and TNF-α will be analyzed in GCF and saliva samples by ELISA.
590 studies on the registry are indexed under Gingivitis; 104 are open to participants now.
This study's enrollment of 88 is close to the median of 90 across 104 observational studies indexed under Gingivitis.
Browse Gingivitis studies →Aydin Adnan Menderes University is the lead sponsor of 236 studies on the registry; 54 are open to participants now.
Counted across the registry records on this site, refreshed daily.
88 Children with diabetes mellitus and systemically healty children with and without gingivitis.
Exclusion Criteria:
Children with type 1 diabetes mellitus and gingivitis
Diagnostic Test: ELISA
Children with type 1 diabetes mellitus and healthy gingiva
Diagnostic Test: ELISA
Systemically healthy patients with gingivitis
Diagnostic Test: ELISA
Systemically healthy patients with healthy gingiva
Diagnostic Test: ELISA
Enzim linked immunoabsorbant assay
Interleukin-18 level
IL-18
Time frame: Baseline
Tnf-alpha level
Tnf-Alpha
Time frame: Baseline
This study is completed, as verified in Jul 2019. You cannot join it, but the record below documents what was studied.
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Aydin Adnan Menderes University