An interventional study of Medical thoracoscopy in Empyema, sponsored by Assiut University. Status unknown. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2019-03-05.
Sponsored by Assiut University · Not applicable, Interventional, and Other
Pleural empyema : is a collection of pus in the pleural cavity caused by microorganisms, usually bacteria.[1]
Medical thoracoscopy has played a marginal role in the treatment of empyema for a long time, but has become more and more established in recent years. It can be per-formed in analgo-sedation in a bronchoscopy suite. It is minimally invasive and costs are much lower compared to surgical VATS. The diagnostic and therapeutic power seems to be comparable to VATS, since several studies show success rates with medical thoracoscopy between 73 and 100% (2, 3) .
Study Setting: Assuit university hospital - Chest department. endoscopy unit . the subjects will under go the following :
Pleural fluid aspiration and analyses .
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Medical thoracoscopy with single-port-of-entry technique will be performed in the bronchoscopy unit under local anesthesia and conscious sedation using midazolam (2 mg) or bethdein.
The indications for removal of chest tubes will be absence of air leakage and cessation of fluid flow (100-150 mL daily).
medical thoracoscopy or tube thoracostomy .
38 studies on the registry are indexed under Empyema; 11 are open to participants now.
This study's planned enrollment of 60 is below the median of 92 across 28 interventional studies indexed under Empyema.
Browse Empyema studies →Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
patients having empyema will undergo medical thoracoscopy as follow : With the closed biopsy forceps, step by step, fibrinous septae will be perforated, the pleural space was irrigated with saline and fluid and fibrinopurulent material were aspirated and removed from the pleural cavity, the entire pleural cavity was inspected and biopsies were obtained from suspicious areas carefully by the biopsy forceps under vision. Multiple lesions were encountered, multiple biopsies were taken \& If no lesion, biopsy from parietal pleura was obtained from any sites. the intervention : is breaking the septation within the loculated empyema
Other: Medical thoracoscopy
after confirmation of diagnosis of empyema Following , a chest tube (gauge 26-28) will be introduced and connected to underwater seal. The wound was then closed around the tube by stitches to fix it in position.
• With the closed biopsy forceps, step by step, fibrinous septae were perforated, the pleural space was irrigated with saline and fluid and fibrinopurulent material were aspirated and removed from the pleural cavity, the entire pleural cavity was inspected and biopsies were obtained from suspicious areas carefully by the biopsy forceps under vision. Multiple lesions were encountered, multiple biopsies were taken \& If no lesion, biopsy from parietal pleura was obtained from any sites.
Medical cure without secondary Intervention
medical cure will be defined as radiologic confirmation of successful pleural drainage (i.e. reduction of the size of the pleural fluid on the chest X-ray and chest ultrasound )with no need for further treatment by r surgical interventions) objective evidence of sepsis resolution (improvement in temperature and clinical condition and decreasing inflammatory laboratory markers .and decrease of amount of fluid discharge less than (50-100)cc per day .
Time frame: up to 14 days .
Duration of hospital stay
Reduction in hospital stay in group with medical thoracoscopy in comparison to the group with simple chest tube
Time frame: up to 14 day .
Adverse events
such as bleeding , sever pain , persistence air leak
Time frame: within 24 hour after medical thoracoscopy
No study locations are listed for this record.
This study is status unknown, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.
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