An interventional study of Intermittent Perturbation to Continuous Perturbation and Continuous Perturbation to Intermittent Perturbation in Stroke, Spinocerebellar Ataxia and Cerebral Stroke, sponsored by University of Florida. Withdrawn. Open to participants aged 21 Years to 100 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-06-15.
Sponsored by University of Florida · Not applicable, Interventional, and Treatment
This study will test laryngeal adaptation in speech and swallowing function in healthy adults, in patients with cerebral stroke, and in patients with spinocerebellar ataxia type 6. The findings from this proposal will be the first step toward implementing rehabilitation techniques that help patients to prevent speech and swallowing errors before they occur.
8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.
Browse Stroke studies →University of Florida is the lead sponsor of 1,287 studies on the registry; 199 are open to participants now.
Of its 180 completed or terminated interventional studies of FDA-regulated products, 143 (79%) have results posted.
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Patient Inclusion Criteria:
All stroke and ataxia
Ataxia
Stroke
Stroke and ataxia with speech and swallowing disorders
Patient Exclusion Criteria:
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Device: Intermittent Perturbation to Continuous Perturbation · Device: Continuous Perturbation to Intermittent Perturbation
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Device: Intermittent Perturbation to Continuous Perturbation · Device: Continuous Perturbation to Intermittent Perturbation
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Device: Intermittent Perturbation to Continuous Perturbation · Device: Continuous Perturbation to Intermittent Perturbation
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Device: Intermittent Perturbation to Continuous Perturbation · Device: Continuous Perturbation to Intermittent Perturbation
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Device: Intermittent Perturbation to Continuous Perturbation · Device: Continuous Perturbation to Intermittent Perturbation
Manipulate the Movement Planning Period (MPP), by interrupting sensory predictions by removing e-stim during the inter-trial interval (Intermittent Perturbation), followed by a washout/de-adaptation period.
Also known as: I to C Paradigm
Manipulate the Movement Planning Period (MPP), by keep sensory input about the perturbation constant by maintaining e-stim during the inter-trial interval.
Also known as: C to I Paradigm
Laryngeal Adaptation in Speech
To differentiate laryngeal adaptation during speech among cerebral stroke, SCA6, and healthy controls when vocal loudness is perturbed with expiratory loading.
Time frame: Day 1
Laryngeal Adaptation in Swallowing
To differentiate laryngeal adaptation among cerebral stroke, SCA6, and healthy controls when swallowing is perturbed with neck surface electrical stimulation to restrict laryngeal elevation.
Time frame: Day 1
No study locations are listed for this record.
Ran from Aug 2018 to primary completion in Aug 2019, 12 months.
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This study is withdrawn, as verified in Jun 2021. You cannot join it, but the record below documents what was studied.
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