A Phase 4 interventional study of Silver nanoparticle/Calcium hydroxide and Silver Nanoparticles in gel form in Postoperative Pain, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 20 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-10-19.
Sponsored by Cairo University · Phase 4, Interventional, and Treatment
To assess the Postoperative Pain after using Silver Nanoparticles with and without Calcium Hydroxide as an Intracanal Medication in Patients with necrotic pulp (RCT)
When the treatment itself appears to initiate the onset of pain and/or swelling, the result can be very distressing to both the patient and the operator. Patients might even consider postoperative pain and flare-up as a benchmark against which the clinician's skills are measured. Prevalence of postoperative pain or flare-up is, therefore, one of the influencing factors when making a clinical decision. Better management of postoperative pain increases the patients' confidence in dentist's skills and gives positive attitude toward dental profession. In cases with necrotic pulp, the incidence of pain becomes higher, hence testing which intracanal medication is more effective in decreasing the bacteria present within the root canal and subsequently pain is crucial.
149 studies on the registry are indexed under Dental Pulp Necrosis; 39 are open to participants now.
This study's enrollment of 30 is below the median of 44 across 139 interventional studies indexed under Dental Pulp Necrosis.
Browse Dental Pulp Necrosis studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients receiving combined Silver nanoparticle/Calcium hydroxide administered as intracanal medication at the first visit after cleaning and shaping
Combination Product: Silver nanoparticle/Calcium hydroxide
Patients receiving silver nanoparticles in gel form administered as intracanal medication at the first visit after cleaning and shaping
Drug: Silver Nanoparticles in gel form
Patients receiving calcium hydroxide intracanal medication at the first visit after cleaning and shaping
Drug: Calcium Hydroxide Intracanal medication
Intracanal Medication composed of combined silver nanoparticles with calcium hydroxide
Intracanal medication composed of silver nanoparticles in gel form
Calcium hydroxide intracanal medication
Change in post-operative pain
Numerical (0-10)
Time frame: Intra-appointment and post obturation at 4, 24, 48, 72, 96 hours
Intracanal Bacterial count reduction
Quantification of Colony forming units per milliliter of agar medium (CFU/mL)
Time frame: 1 week
Number of analgesic tablets taken by the patient after endodontic treatment
Number
Time frame: Within 4 days after the first session and after 1 week from first treatment session
Plan to share: Yes — Participant data will be made available
Supporting information: Study protocol, Icf
This study is completed, as verified in Oct 2020. You cannot join it, but the record below documents what was studied.
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Cairo University