An interventional study of Intracanal medication in Immature Permanent Teeth With Open Apex and Pulp Necrosis, sponsored by Mansoura University. Recruiting at 1 site in Egypt. Open to participants aged 8 Years to 18 Years. Per ClinicalTrials.gov, last updated 2026-09-23.
Sponsored by Mansoura University · Not applicable, Interventional, and Treatment
Among 43 studies in Dental Pulp Necrosis with a site in Egypt — 12 open to participants now, 16 under way, 1 of them phase 3. Dental Pulp Necrosis · Egypt.
Among the 43 studies in Dental Pulp Necrosis with a site in Egypt, this one is the 38th largest by planned enrollment, is one of 7 that started in 2026, is one of 31 with no phase, reaches primary completion later than 11 of the 15 other live ones, and was the 42nd registered.
157 studies on the registry are indexed under Dental Pulp Necrosis; 44 are open to participants now.
Browse Dental Pulp Necrosis studies →12 of the 43 studies in Dental Pulp Necrosis with a site in Egypt are open now. Recruiting first, the newest first:
October 6 University · Sites in Egypt
Ages 21–50
Cairo University · Sites in Egypt
Ages 18–40 · Healthy volunteers
Kafrelsheikh University · Sites in Egypt
Ages 9–15 · Healthy volunteers
Ain Shams University · Sites in Egypt
Ages 5–7 · Healthy volunteers
Mansoura University · Sites in Egypt
Ages 20–60 · Healthy volunteers
A study can be open while its sites in Egypt have not opened yet or have stopped. Only those recruiting at a site in Egypt →
Of the 15 Dental Pulp Necrosis studies recruiting now, 6 (40%) set no upper age limit and 7 (47%) stop at 75 or younger; 4 take children under 18; 5 take healthy volunteers.
This study: 8 Years to 18 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
43 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 2 · Phase 2 6 · Phase 3 1 · Phase 4 4
First in 2016; this study’s year is marked. 7 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 20 is below the median of 45 across 148 interventional studies indexed under Dental Pulp Necrosis.
Median enrollment 40 across the 43 interventional studies. Of the 22 that completed or were terminated, 1 (5%) have results posted.
This tab as a report to print or save as PDF → With an account.
None of the 43 has an industry lead sponsor. The 10 most frequent:
Mansoura University is the lead sponsor of 1,119 studies on the registry; 183 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Mansoura University has 8 studies filed under Dental Pulp Necrosis — fewer than ten, so there is no comparison to draw.
9 of the studies in Dental Pulp Necrosis with a site in Egypt that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07371416Mansoura UniversityRegenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty Acids | 2026-12 |
| NCT07747753Ahmed Hesham Abdelmohaimen RezkComparison of Post-operative Pain and Levels of MMP -9 Following Root Canal Irrigation With Sodium Hypochlorite Versus Cold Atmospheric Plasma in Patient With Necrotic Single Rooted Teeth: Randomized Clinical Trial | 2027-01 |
| NCT07897591October 6 UniversityConventional and Nano-Metronidazole Irrigation With/Without Activation in Necrotic Teeth With Apical Periodontitis | 2027-01 |
| NCT07790796Future University in EgyptEvaluation of Post-operative Pain and Bacterial Load Reduction After Application of Three Intra-canal Medications (Cocoa Husk Versus Calcium Hydroxide With and Without Cocoa) in Necrotic Mandibular First Molar. | 2027-01-06 |
| NCT07388888Ain Shams UniversityAntibacterial Effect of Two Different Intracanal Medicaments and Their Effect on Post-operative Pain | 2027-02 |
Add all 9 to your calendar (.ics) → With an account.
Among the 43 studies in Dental Pulp Necrosis with a site in Egypt, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study assess the ability of Asiaticoside based Intracanal medication compared to the commonly used Intracanal medicament ( calcium hydroxide Ca(OH) 2) on the outcome of the revascularization process in immature permanent teeth with pulp necrosis
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Procedure: Intracanal medication
Procedure: Intracanal medication
Intracanal Medication for 3 weeks in Revascularization Process
Increase In Root Length
Radiographic increase in root length ( Millimeters(mm))
Time frame: 12 monthsl
Increase In Dentinal Wall Thickness
Radiographic increase in dentinal wall thickness measured using digital image analysis (Millimeters(mm))
Time frame: 12 months
Periapical Bone Formation
Radiographic evidence of periapical bone formation
Time frame: 12 months
Start is estimated for Oct 2026; primary completion for Feb 2027, 4 months later.
Of 66 non-industry interventional studies with no phase under Dental Pulp Necrosis, half reached primary completion within 16 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 35. This study's planned 4 months is below that.
Counting every sponsor, half of 67 studies reached it within 15 months; a quarter within 9 and three quarters within 31.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.