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CompletedNCT03681665Updated Sep 29, 2020

Use of Iterative Reconstruction Method in Ultralow-dose CT for Follow-up of Patients With Intraabdominal Abscess: Comparison With Standard Dose CT

An observational study in Abdominal Abscess, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 100 Years. Per ClinicalTrials.gov, last updated 2020-09-29.

Sponsored by Yonsei University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
20
Ages
20 Years to 100 Years
Sex
All
01

Study summary

Increasing radiation exposure by medical examinations is getting more concerns. For optimal medical imaging, reducing radiation exposure with preservation image quality is important. One of the solutions is use of iterative recontruction of CT examination. In this study, the investigators aimed to investigate the clinical feasibility of ultralow dose abdominopelvic CT with iterative reconstruction in patients with intraabdominal abscess. Patients with intrabdominal abscess usually undergo multiple CT examinations to evaluate treatment response. Therefore, ultralow dose CT can reduce unnecessary radiation exposure in these patients.

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Conditions studied

  • Abdominal Abscess

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03

In context

Abdominal Abscess

31 studies on the registry are indexed under Abdominal Abscess; 5 are open to participants now.

Browse Abdominal Abscess studies →

Lead sponsor

Yonsei University is the lead sponsor of 1,418 studies on the registry; 241 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with suspected abdominal abscess from a tertiary care clinic.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. patients who underwent standard dose CT for suspected intraabdominal abscess
  2. patients who need follow-up CT to evaluate treatment response of abscess 3) Adult patient, 4) patients who agreed this study protocol

Exclusion criteria

Exclusion Criteria:

  1. pregnancy
  2. patients with poor renal function ( \< 30 mL/min/1/73m2)
  3. Patients who have allergy to CT contrast media
  4. Patients who are not cooperative (e.g., dementia)
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

GFR and eGFR (kidney filtering)

GFR (glomerular filtration rate) is how much blood the kidneys filter each minute. It is usually estimated from a blood test — eGFR, by formulas such as CKD-EPI or MDRD — and some studies ask for it to be measured directly instead. Usually given in mL/min/1.73 m².

Check the method, the units and the minimum the study states. A value of 90 or above is in the normal-or-high range, but kidney damage can show in other tests too.

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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
20 participants (actual)
Patient registry
No

Groups and cohorts

  • Abscess

    Patients group with abdominal abscess

    Other: ultralow dose abdominopelvic CT

Interventions

  • Otherultralow dose abdominopelvic CT

    In the patient cohort with abdominal abscess, ultralow dose abdominopelvic CT will be performed as a follow-up protocol. Ultralow dose CT has approximately 80\~90% reduced radiation dose compared to standard dose CT.

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What researchers measure

Primary outcomes

  1. Score of subjective image quality of CT image

    Score of subjective image quality of CT images consists of overall subjective image quality, noise, diagnostic ability, and artifact.

    Time frame: 1 month

Secondary outcomes

  1. Effective radiation dose: CTDIvol(volume CT dose index), DLP(dose length product), effective dose(DLPx0.015)

    Effective radiation dose between standard dose CT and ultra-low dose CT will be compared

    Time frame: 1 month

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Study locations

1 site
  • Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine
    Seoul, 03722, Korea, Republic of
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 29, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03681665
Lead sponsor
Yonsei University
Responsible party
Sponsor
First posted
Sep 24, 2018
Start date
Jun 29, 2018
Primary completion
Mar 18, 2019
Completion
Mar 18, 2019
Last update
Sep 29, 2020

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.

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Discussion

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