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CompletedNCT03647397Updated May 17, 2019

PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress

An interventional study of Photo Electrochemical Oxidation (PECO) for Air Purification in Asthma, Pneumonia and Respiratory Distress Syndrome, sponsored by Molekule. Completed at 1 site in United States. Open to participants aged 1 Year to 17 Years. Per ClinicalTrials.gov, last updated 2019-05-17.

Sponsored by Molekule · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
274
Allocation
Not applicable
Ages
1 Year to 17 Years
Sex
All
01

Study summary

This study will investigate the efficacy of a novel air purification technology, Photo Electrochemical Oxidation (PECO), has on pediatric patients hospitalized for respiratory distress. The study will take place at Mercyhealth Hospital - Rockton Avenue where all 23 pediatric rooms will be outfitted with portable PECO air purifying units. The main outcomes are the length of stay and progression to ICU, which will be compared with historical controls.

Read the detailed description

The goal of this study is to assess whether using PECO to purify air in a hospital can improve health outcomes for pediatric patients with respiratory distress.

The results of this study will be used in three primary ways:

  1. As evidence to support an installation of PECO in hospital HVAC systems to improve the standard of care for patients with respiratory distress
  2. Towards dissemination efforts through publication in a peer-reviewed journal and presentation at national and international conferences
  3. For informing healthcare providers and stakeholders

There are no plans to repeat this study with other hospital partners

02

Conditions studied

  • Asthma
  • Pneumonia
  • Respiratory Distress Syndrome

Keywords

  • asthma
  • environmental intervention
  • respiratory distress
  • pediatric hospitalization
  • pneumonia
  • bronchiolitis
03

In context

Pneumonia

2,044 studies on the registry are indexed under Pneumonia; 283 are open to participants now.

This study's enrollment of 274 is above the median of 106 across 1,247 interventional studies indexed under Pneumonia.

Browse Pneumonia studies →

Lead sponsor

Molekule is the lead sponsor of 2 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
1 Year to 17 Years
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

Inclusion Criteria: All pediatric patients who are admitted to the Mercyhealth Hospital - Rockton Avenue following the Start Date and have infectious or non-infectious respiratory distress as defined by the following ICD codes will be included in the study:

  • J00-J06: Acute upper respiratory infections
  • J09-J18: Influenza and pneumonia
  • J20-J22: Other acute lower respiratory infections
  • J30-J39: Other diseases of upper respiratory tract
  • J40-J47: Chronic lower respiratory diseases
  • J60-J70: Lung diseases due to external agents
  • J80-J84: Other respiratory diseases principally affecting the interstitium
  • J85-J86: Suppurative and necrotic conditions of the lower respiratory tract
  • J90-J94: Other diseases of the pleura
  • J95-J95: Intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

Exclusion Criteria:

  • Any patient admitted to the NICU
  • Patients in the ER only
  • Any patient with non-respiratory conditions
  • Adults
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
274 participants (actual)

Study arms

  • Experimental
    PECO

    All pediatric patients admitted for respiratory distress will have the intervention of Photo Electrochemical Oxidation (PECO) for Air Purification.

    Device: Photo Electrochemical Oxidation (PECO) for Air Purification

Interventions

  • DevicePhoto Electrochemical Oxidation (PECO) for Air Purification

    PECO air purifiers from Molekule will be placed in every patient room. Health metrics will be tracked for patients whose diagnosis is respiratory distress.

06

What researchers measure

Primary outcomes

  1. Length of stay

    Total length of hospital stay for patient

    Time frame: 5 months

Secondary outcomes

  1. Readmission rate

    Rate of readmission within 30 days of discharge

    Time frame: 1 months

07

Study locations

1 site
  • Mercyhealth Hospital - Rockton Avenue
    Rockford, Illinois 61103, United States
08

References and documents

Study documents

  • Study protocol · Oct 10, 2018

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 17, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03647397
Lead sponsor
Molekule
Collaborators
Mercy Health System
Responsible party
Sponsor
First posted
Aug 27, 2018
Start date
Aug 8, 2018
Primary completion
Dec 31, 2018
Completion
Dec 31, 2018
Last update
May 17, 2019

Study contacts

Nikhil Rao
principal investigator · Molekule

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2019. You cannot join it, but the record below documents what was studied.

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