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CompletedNCT03532919Updated Dec 17, 2018

Heart and Renal Failure in Hip Fracture Surgery

An observational study in Hypotension, Hip Fractures and Renal Insufficiency, sponsored by Sahlgrenska University Hospital. Completed at 1 site in Sweden. Per ClinicalTrials.gov, last updated 2018-12-17.

Sponsored by Sahlgrenska University Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
105
Sex
All
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Study summary

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as well as renal failure noted by Changes in Serum Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

Read the detailed description

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as awell as renal failure noted by Changes in S Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as a step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

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Conditions studied

  • Hypotension
  • Hip Fractures
  • Renal Insufficiency
  • Heart Injuries
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In context

Renal Insufficiency

1,995 studies on the registry are indexed under Renal Insufficiency; 173 are open to participants now.

This study's enrollment of 105 is below the median of 149 across 394 observational studies indexed under Renal Insufficiency.

Browse Renal Insufficiency studies →

Lead sponsor

Sahlgrenska University Hospital is the lead sponsor of 259 studies on the registry; 68 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with an acute hip fracture classified as being ASA 3 or more

Inclusion criteria

  • Hip fracture patient to be operated upon Classified as being ASA 3 or more

Exclusion criteria

Exclusion Criteria:

  • Not forfilling inclusion Criterias
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
105 participants (actual)
Target follow-up
12 Months
Patient registry
Yes
Biospecimen retention
Samples without dna

Interventions

  • Diagnostic testSerum Tropinin

    Blodsamples will be taken 4 times from preoperatively to 2 Days postoperatively

    Also known as: Serum Cystatin C

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What researchers measure

Primary outcomes

  1. Mortality

    post surgery

    Time frame: 90 days

Secondary outcomes

  1. Serum concentrations of Troponin, NTproBNP, Creatinin and Cystatin C

    Relations between values and mortality at 30 and 90 days

    Time frame: 90 days

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Study locations

1 site
  • Sahlgrenska University Hospital
    Molndal, Vastra Gotaland 431 80, Sweden
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 17, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03532919
Lead sponsor
Sahlgrenska University Hospital
Responsible party
Bengt Nellgard (Associate professor, Sahlgrenska University Hospital) — Principal investigator
First posted
May 22, 2018
Start date
Feb 1, 2018
Primary completion
Aug 1, 2018
Completion
Dec 1, 2018
Last update
Dec 17, 2018

Study contacts

Bengt M Nellgard, MD PhD
principal investigator · SahlgrenskaUniversity Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2018. You cannot join it, but the record below documents what was studied.

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