An observational study in Surgery, Surgical Blood Loss and Anemia, sponsored by Ottawa Hospital Research Institute. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-09-24.
Sponsored by Ottawa Hospital Research Institute · Observational
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The objective is to measure the adjusted association between preoperative anemia and total hospital costs. We hypothesize that patients with anemia before surgery will have higher hospitalization costs than people without anemia.
This study will examine the association between preoperative anemia (hematocrit less than 0.39; low blood counts) and hospital total costs from elective colorectal surgery. Total costs will be defined as the combination of direct and indirect costs ascertained using standardized patient-level costing algorithms (i.e. the standard way that hospital measure their costs). Adjustment will be made for factors that are likely to influence both the presence of anemia and costs of care.
213 studies on the registry are indexed under Blood Loss, Surgical; 40 are open to participants now.
This study's enrollment of 851 is above the median of 154 across 43 observational studies indexed under Blood Loss, Surgical.
Browse Blood Loss, Surgical studies →Ottawa Hospital Research Institute is the lead sponsor of 547 studies on the registry; 99 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All adults having elective colorectal surgery with national surgical quality improvement program data available
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Exclusion Criteria:
People with a preoperative hematocrit less than 0.39
Other: Anemia
People with a preoperative hematocrit greater than or equal to 0.39
Hematocrit less than 0.39
Total Hospital Costs
Direct and indirect costs accrued during the index hospitalization. Costs were measured using standard and validated algorithms, standardized to 2016 CAD. This method accounts for a patient's resource intensity weight, their case mix group, as well as fixed patient costs (e.g., medications, investigations) and indirect costs to the hospital based on patient's location of care (intensive care unit versus ward) and length of stay.
Time frame: Hospital admission to date of discharge from hospital, or 365 days after admission, whichever came first
Length of Stay
Number of days in hospital after surgery
Time frame: Date of surgery to date of hospital discharge, or up to one year after surgery (whichever comes first)
Red Blood Cell Transfusion
Any red blood cell transfusion received
Time frame: Hospital admission to date of surgery, or 365 days after admission, whichever came first
| Milestone | Anemic | Non-anemic |
|---|---|---|
| Started | 381 | 470 |
| Completed | 381 | 470 |
| Not completed | 0 | 0 |
Direct and indirect costs accrued during the index hospitalization. Costs were measured using standard and validated algorithms, standardized to 2016 CAD. This method accounts for a patient's resource intensity weight, their case mix group, as well as fixed patient costs (e.g., medications, investigations) and indirect costs to the hospital based on patient's location of care (intensive care unit versus ward) and length of stay.
| Dollars | Anemic | Non-anemic |
|---|---|---|
| Total Hospital Costs | 23,667 ± 32,210 | 17,100 ± 10,822 |
Number of days in hospital after surgery
| Days | Anemic | Non-anemic |
|---|---|---|
| Length of Stay | 12.4 ± 17.5 | 8.5 ± 7.5 |
Any red blood cell transfusion received
| Participants | Anemic | Non-anemic |
|---|---|---|
| Red Blood Cell Transfusion | 88 | 18 |
Collected over AEs were not collected. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Anemic | — | — | — |
| Non-anemic | — | — | — |
| Age, Customized(Participants) | Anemic | Non-anemic | Total |
|---|---|---|---|
| Age — < 65 | 123 | 272 | 395 |
| Age — 65-74 | 105 | 117 | 222 |
| Age — 75-84 | 114 | 67 | 181 |
| Age — >84 | 39 | 14 | 53 |
| Sex: Female, Male(Participants) | Anemic | Non-anemic | Total |
|---|---|---|---|
| Female | 214 | 181 | 395 |
| Male | 167 | 289 | 456 |
| Independent Functional Status(Participants) | Anemic | Non-anemic | Total |
|---|---|---|---|
| Count of participants | 353 | 467 | 820 |
| Elixhauser comorbidity index(Index) | Anemic | Non-anemic | Total |
|---|---|---|---|
| Mean | 6.16 ± 5.98 | 5.50 ± 5.89 | 6 ± 6 |
| Procedural Index for Mortality Risk (PIMR) Score(Number of procedural risk points) | Anemic | Non-anemic | Total |
|---|---|---|---|
| Mean | 0.47 ± 1.39 | 0.17 ± 0.70 | 0.3 ± 1.1 |
| American Society of Anesthesiology (ASA) Score(Participants) | Anemic | Non-anemic | Total |
|---|---|---|---|
| I-II | 51 | 142 | 193 |
| III | 260 | 302 | 562 |
| IV-V | 70 | 26 | 96 |
No study locations are listed for this record.
Plan to share: No
Ran from Jan 2010 to primary completion in Dec 2016, 83 months.
Results were first posted in Sep 2024, 7 years 9 months after primary completion.
Of 23 observational studies under Blood Loss, Surgical, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 60. This study's 83 months is above that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.
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