A Phase 2/3 interventional study of Rutin in combination with Vitamin C and Vitamin C in Type 2 Diabetes Mellitus, sponsored by Ain Shams University. Completed at 1 site in Egypt. Open to participants aged 35 Years and older. Per ClinicalTrials.gov, last updated 2018-05-16.
Sponsored by Ain Shams University · Phase 2/3, Interventional, and Treatment
Among 130 studies in Diabetes Mellitus, Type 2 with a site in Egypt — 18 open to participants now, 21 under way, 5 of them phase 3. Diabetes Mellitus, Type 2 · Egypt.
Among the 130 studies in Diabetes Mellitus, Type 2 with a site in Egypt, this one is the 80th largest by enrollment of the 98 interventional ones that give a count, is one of 11 that started in 2018, is one of 4 in phase 2/3, and was the 28th registered.
10,378 studies on the registry are indexed under Diabetes Mellitus, Type 2; 1,406 are open to participants now.
Browse Diabetes Mellitus, Type 2 studies →18 of the 130 studies in Diabetes Mellitus, Type 2 with a site in Egypt are open now. Recruiting first, the newest first:
New Valley University · Sites in Egypt
Ages 40+ · Healthy volunteers
Mona Mohamed Abdelkhalek · Sites in Egypt
Ages 60–75
Cairo University · Sites in Egypt
Ages 35–45 · Women only
South Valley University · Sites in Egypt
Ages 40–60
Tanta University · Sites in Egypt
Ages 18+
A study can be open while its sites in Egypt have not opened yet or have stopped. Only those recruiting at a site in Egypt →
Of the 883 Diabetes Mellitus, Type 2 studies recruiting now, 373 (42%) set no upper age limit and 384 (43%) stop at 75 or younger; 52 take children under 18; 203 take healthy volunteers.
This study: 35 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
130 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 4 · Phase 2 12 · Phase 3 19 · Phase 4 25
First in 2006; this study’s year is marked. 11 started in 2018.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 53 is below the median of 80 across 8,350 interventional studies indexed under Diabetes Mellitus, Type 2.
Median enrollment 80 across the 98 interventional studies, 198 across the 32 observational. Of the 91 that completed or were terminated, 14 (15%) have results posted.
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26 of 130 have an industry lead sponsor. The 10 most frequent:
Ain Shams University is the lead sponsor of 1,953 studies on the registry; 430 are open to participants now.
Of its 35 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Ain Shams University has 9 studies filed under Diabetes Mellitus, Type 2 — fewer than ten, so there is no comparison to draw.
4 of the studies in Diabetes Mellitus, Type 2 with a site in Egypt that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07934225Phase 3Fayoum UniversityAlpha-Lipoic Acid Added to Dapagliflozin and Insulin Resistance in Type 2 Diabetes | 2027-08-01 |
| NCT07916428Alexandria UniversityAI-Based Model for Predicting Type 2 Diabetes Risk Using Lifestyle Factors Among Senior Nursing Students | 2026-12 |
| NCT07926074Alexandria UniversityAI Chatbot Mobile App for Self-Management in Type 2 Diabetes | 2027-05-09 |
| NCT07891234Sherihan AboElyazed Mohamed KhalilEffect of SGLT2 Inhibitor on Metabolic-Dysfunction-Associated Fatty Liver Disease in Patients With Insulin Resistance | 2027-10-01 |
Add all 4 to your calendar (.ics) → With an account.
Among the 130 studies in Diabetes Mellitus, Type 2 with a site in Egypt, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The objective of this study is to investigate the effect ofRutin and Vitamin C combination in comparison with vitamin C alone on the oxidative and antioxidative status , insulin resistance and lipid profile in type 2 diabetic patients.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Patients' age 35 years or older having type 2 diabetes mellitus.
Exclusion Criteria:
Pregnant and breast feeding females
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
patients will receive Rutin 60 mg in combination with vitamin C 160 mg three times daily in addition to usual antidiabetic treatment for 8 weeks..
Dietary Supplement: Rutin in combination with Vitamin C
patients will receive vitamin C 500 mg once daily in addition to usual antidiabetic treatment for 8 weeks.
Dietary Supplement: Vitamin C
patients will receive their usual antidiabetic treatment only for 8 weeks.
Drug pages: Rutin · Ascorbic Acid
Rutin and Vitamin C will be supplied as tablets containing 60 mg Rutin and 160 mg Vitamin C. The use of Rutin and Vitamin C will be under the trade name of RUTA C 60 ® manufactured by KAHIRA PHARM.\& CHEM. IND. Company
Vitamin C will be supplied as capsules containing500 mg of Vitamin C. The use of Vitamin C will be under the trade name of C-Retard ® manufactured by HIKMA Quality Company.
Also known as: Ascorbic acid
Oxidative stress marker (MDA) and antioxidant capacity (SOD) in diabetic patients
Effect of Rutin and vitamin C combination or vitamin C alone on oxidative stress marker (MDA) and on antioxidant capacity (SOD) in diabetic patients after 8 weeks of treatment.
Time frame: Two months
Insulin resistance in diabetic patients .
Effect of Rutin and vitamin C combination or vitamin C alone on insulin resistance in diabetic patients before i and after treatment for 8 weeks .
Time frame: Two months
Lipid profile in diabetic patients (TC,TG,HDL-c,LDL-c).
Impact of Rutin and vitamin C combination or vitamin C alone on lipid profile in diabetic patients (TC,TG,HDL-c,LDL-c).
Time frame: Two months
Quality of life of diabetic patients and this will be evaluated by using Quality of Life Questionnaire (Short Form 36 questions (SF-36)) .
The effect of Rutin and vitamin C combination on quality of life of diabetic patients before and after treatment for 8 weeks and this will be evaluated by using Quality of Life Questionnaire (Short Form 36 questions (SF-36)) .
Time frame: Two months
Ran from Feb 2018 to primary completion in May 2018, 2 months.
Of 26 non-industry phase 2/3 interventional studies under Diabetes Mellitus, Type 2, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 30. This study's 2 months is below that.
Counting every sponsor, half of 32 studies reached it within 22 months; a quarter within 13 and three quarters within 31.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Rutin · Ascorbic Acid