An interventional study of NW training and Placebo in Vitamin D3 Deficiency, sponsored by Gdansk University of Physical Education and Sport. Completed at 2 sites in Poland. Open to participants aged 15 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-05-11.
Sponsored by Gdansk University of Physical Education and Sport · Not applicable, Interventional, and Prevention
Among 64 studies in Motor Activity with a site in Poland — 17 open to participants now, 24 under way, none of them phase 3. Motor Activity · Poland.
Among the 64 studies in Motor Activity with a site in Poland, this one is the 23rd largest by enrollment of the 47 interventional ones that give a count, is one of 6 that started in 2018, is one of 41 with no phase, and was the 12th registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
Browse Motor Activity studies →17 of the 64 studies in Motor Activity with a site in Poland are open now. Recruiting first, the newest first:
Poznan University of Physical Education · Sites in Poland
Wageningen University · Sites in Poland, Germany, Netherlands
The Jerzy Kukuczka Academy of Physical Education in Katowice · Sites in Poland
Medical University of Bialystok · Sites in Poland
Zealand University Hospital · Sites in Poland, Denmark, Germany and 2 more countries
A study can be open while its sites in Poland have not opened yet or have stopped. Only those recruiting at a site in Poland →
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 15 Years to 80 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
64 studies; the count open now beside each. This study's row is marked.
First in 2003; this study’s year is marked. 6 started in 2018.
This study's enrollment of 100 is above the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Median enrollment 100 across the 47 interventional studies, 100 across the 17 observational. Of the 33 that completed or were terminated, 3 (9%) have results posted.
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5 of 64 have an industry lead sponsor. The 10 most frequent:
Gdansk University of Physical Education and Sport is the lead sponsor of 37 studies on the registry; 11 are open to participants now.
Gdansk University of Physical Education and Sport has 5 studies filed under Motor Activity — fewer than ten, so there is no comparison to draw.
8 of the studies in Motor Activity with a site in Poland that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07752459Poznan University of Physical EducationPhysiological Responses to Basketball-Specific Interval Exercise in Female Basketball Players | 2026-11-30 |
| NCT07529132Medical University of BialystokChanges in Energy Expenditure in Response to Physical Activity in Healthy Adults | 2026-12 |
| NCT06606769Poznan University of Physical EducationPhysical Activity Guarantees Bone Density. | 2026-12-31 |
| NCT06682741Poznan University of Physical EducationComparison of Different Training Programs on Cognitive Function | 2026-12-31 |
| NCT06606678Poznan University of Physical EducationThe Role of Regular Physical Activity in Enhancing Metabolic Health, Reducing Inflammation, and Improving Gut Function | 2026-12-31 |
Among the 64 studies in Motor Activity with a site in Poland, from their registry updates:
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Physical activity is a recommended, indispensable element of a healthy lifestyle as well as a countermeasure against many diseases often accompanied by the acute or chronic low grade inflammation. Papers published in recent years have demonstrated the anti-inflammatory effect of exercise. Based on current knowledge of the topic, own experience and preliminary work, it is expected the proposed research to provide information on the mechanism either determining or limiting pro-healthy effects of exercise in different age groups of people. Three different training programmes will be investigated. Specific goals of the project include the following:
The mechanism behind the anti-inflammatory effect of exercise is not fully understood. In some cases physical activity has proven almost/completely ineffective in reducing systemic inflammation. Thus, evaluating factors, which modify this response, is of particular significance. One of them may be related to iron metabolism. It is has been suggested that regular training reduces body iron stores, which can contribute to the anti-inflammatory response. Consequently, one of the anti-inflammatory effects of exercise can be related to changes in iron metabolism. Nevertheless, our preliminary data demonstrated that eight months of Nordic Walking training did not reduce body iron stores in approx. 25% of subjects, even if some of them were characterized by high blood ferritin (good indicator of body iron stores). This may be related to the effect of exercise on the concentration of hepcidin (main regulator of iron absorption, which acts as a negative regulator of iron efflux). It is well documented that a single bout of exercise induces an increase in blood hepcidin; however, data on the effect of regular training on the hepcidin concentration are limited.
Vitamin D is another factor, which could influence the anti-inflammatory effect of exercise. It has been suggested that individuals involved in physical activity have higher concentrations of 25OHD (indicator of vitamin D status). Vitamin D inhibits the expression of pro-inflammatory cytokines, which is considered the main mechanism of its anti-inflammatory action. It is worth noting that population in Poland is characterized by low status of vitamin D. Thus, it is possible that the anti-inflammatory effect of exercise will be modified by the vitamin status. Moreover, vitamin D has been shown to protect against muscle atrophy both in elderly and younger people. Its concentration has been correlated with muscle strength.
Inflammation has been observed to be associated with an increase of the autophagy-inducing stress protein, HMGB1, which mediates muscle atrophy. Measurement of plasma amino acid profile will be helpful to assess the impact of exercise on muscle proteolysis. Moreover, the link between exercise, vitamin D status and HMGB1 has not yet been established. In addition, a range of interactions induced by exercise involves the release of the newly discovered protein, irisin, form the muscle and its improving effect on the cognitive function through the synthesis of brain-derived neurotrophic factor (BDNF). Data on the effect of regular training on irisin concentration in elderly people is lacking.
Overall, our research interest focuses on the role of the factors mediating the anti-inflammatory effect of exercise and the way they stimulate or inhibit adaptive changes. The proposed project draws on our long experience in investigating the effects of exercise on iron metabolism as well as other physical methods supporting the anti-inflammatory action of physical activity. Latest published papers indicate that the concentration of vitamin D, also in training adaptation, can modulate immunological response to exercise. Therefore, verifying our hypothesis would also allow us to determine if the concentration of vitamin D can limit adaptation to physical activity.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
no illness medical check
Exclusion Criteria:
uncontrolled hypertension (diastolic blood pressure over 100 mmHg), a history of cardiac arrhythmia, cardio-respiratory disorders, advanced osteoporosis, clinical diagnosis of Alzheimer's Disease
exercise and supplementation
Dietary Supplement: NW training · Dietary Supplement: Placebo
Training HICT plus vitamin D
Dietary Supplement: NW training · Dietary Supplement: Placebo · Dietary Supplement: HICT
placebo Vitamin D
Dietary Supplement: NW training
NW training
Also known as: Training, vitamin D
training with placebo
Also known as: Control group
Training and vitamin D
Also known as: resistance training
The influence of vitamin D on physical performance in aging people
To verify if training supported by vitamin D supplementation will bring better effects
Time frame: Values at baseline will be compared to values recorded 12 weeks and 3 months after the training programme.
Plan to share: No — Written-up results of research will be submitted for publication to international journals.
Ran from Jan 2018 to primary completion in Jan 2020, 23 months.
Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 23 months is above that.
Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in May 2021. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Vitamin D
Gdansk University of Physical Education and Sport