A Phase 4 interventional study of CoQ10 supplementation and Placebo supplementation in Health Knowledge, Attitudes, Practice, sponsored by Gdansk University of Physical Education and Sport. Recruiting at 1 site in Poland. Open to male participants aged 30 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-08-26.
Sponsored by Gdansk University of Physical Education and Sport · Phase 4, Interventional, and Treatment
The goal of this clinical trial is to learn if CoQ10 amplifies endurance training-induced myokine and exerkine secretion and if those changes influences cognition in long-distance runners.
Does 4-week high-dosage CoQ10 supplementation increase the secretion of myokine, exerkine sercetion? Does the above-mentioned intervention improve the cognitive function in long distance runners?
Participants will:
Take CoQ10 or a placebo every day for 4 weeks. Visit the laboratory once every 4 weeks for checkups and tests. Keep the participants' food and training diary.
1,573 studies on the registry are indexed under Behavior; 313 are open to participants now.
This study's planned enrollment of 24 is below the median of 120 across 1,197 interventional studies indexed under Behavior.
Browse Behavior studies →Gdansk University of Physical Education and Sport is the lead sponsor of 37 studies on the registry; 11 are open to participants now.
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Exclusion Criteria:
The participants will be treated with CoQ10 supplements
Dietary Supplement: CoQ10 supplementation
The participants will be treated with placebo
Dietary Supplement: Placebo supplementation
Long-distance runners will be supplemented with CoQ10 for 4 weeks in cross-over manner with 4 weeks of wash out period.
Long-distance runners will be supplemented with placebo for 4 weeks in cross-over manner with 4 weeks of wash out period.
Change in cognitive funtions as a result of CoQ10 supplementation measured via cogntitive function test.
The investigators assume that supplementation with CoQ10 will change cognition (measured via cognitive function tests - Stroop Test, Trial Making Test A and Trial Making Test B) in long-distance runners. The results will be obtained as time (seconds) needed to complete tasks while testing.
Time frame: The investigators are going to check this hypothesis after 4 weeks of high-dose supplementation with CoQ10
Change in myokine and exerkine concentration in the blood plasma as a result of CoQ10 supplementation.
The investigators will assess the concentration of blood myokine and exerkine concentration (pg or ug/dl) of blood plasma using the colorimetric method.
Time frame: The investigators are going to check this hypothesis after 4 weeks of high-dose supplementation with CoQ10
Change in aerobic capacity measured via direct test to volitional exhaustion on a motorized treadmill
The investigators assume that supplementation with CoQ10 will change the aerobic capacity (oxygen uptake in ml-1 x min-1 x kg-1) in long-distance runners. The determination of aerobic capacity will be done through progressive test to volitional exhaustion on a motorized treadmill and gas analyzer
Time frame: The investigators are going to check this hypothesis after 4 weeks of high-dose supplementation with CoQ10
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Studies of the drug tested here: Coenzyme Q10
Gdansk University of Physical Education and Sport