An interventional study of Working on Womanhood (WOW) in Anxiety, Anxiety Disorders and Behavioral Symptoms, sponsored by University of Chicago. Completed at 1 site in United States. Open to female participants. Per ClinicalTrials.gov, last updated 2022-08-24.
Sponsored by University of Chicago · Not applicable, Interventional, and Treatment
Among 2,266 studies in Anxiety Disorders with a site in United States — 397 open to participants now, 504 under way, 13 of them phase 3. Anxiety Disorders · United States.
Among the 2,266 studies in Anxiety Disorders with a site in United States, this one is the 13th largest by enrollment of the 2,042 interventional ones that give a count, is one of 96 that started in 2017, is one of 1,607 with no phase, and was the 851st registered.
7,201 studies on the registry are indexed under Anxiety Disorders; 1,682 are open to participants now.
Browse Anxiety Disorders studies →397 of the 2,266 studies in Anxiety Disorders with a site in United States are open now. Recruiting first, the newest first:
University of Wisconsin, Madison · Sites in United States
Children's Mercy Hospital Kansas City · Sites in United States
Columbia University · Sites in United States
Ohio State University · Sites in United States
Weill Medical College of Cornell University · Sites in United States
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 943 Anxiety Disorders studies recruiting now, 416 (44%) set no upper age limit and 460 (49%) stop at 75 or younger; 232 take children under 18; 316 take healthy volunteers.
This study: female · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
2,266 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 119 · Phase 2 200 · Phase 3 95 · Phase 4 88
First in 1983; this study’s year is marked. 96 started in 2017.
This study's enrollment of 5,106 is above the median of 80 across 6,057 interventional studies indexed under Anxiety Disorders.
Median enrollment 69 across the 2,042 interventional studies, 156 across the 215 observational. Of the 1,595 that completed or were terminated, 502 (31%) have results posted.
This tab as a report to print or save as PDF → With an account.
185 of 2,266 have an industry lead sponsor. The 10 most frequent:
University of Chicago is the lead sponsor of 924 studies on the registry; 185 are open to participants now.
Of its 103 completed or terminated interventional studies of FDA-regulated products, 72 (70%) have results posted.
University of Chicago has 6 studies filed under Anxiety Disorders — fewer than ten, so there is no comparison to draw.
218 of the studies in Anxiety Disorders with a site in United States that are under way reach primary completion within a year, 4 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT05552053Phase 3Cedars-Sinai Medical CenterResources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women | 2026-12-31 |
| NCT05474846Phase 3M.D. Anderson Cancer CenterCombination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer | 2027-02-28 |
| NCT06273527Phase 3University of California, San DiegoEnhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33) | 2027-06-01 |
| NCT07123467Phase 3Wayne State UniversityCannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder | 2027-08-31 |
| NCT07718646Oklahoma State UniversityMobile Health Coping Intervention for Mothers Experiencing Food Insecurity | 2026-11 |
Among the 2,266 studies in Anxiety Disorders with a site in United States, from their registry updates:
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The purpose of this study is:
The University of Chicago Crime Lab and Education Lab are partnering with the City of Chicago, Chicago Public Schools, and Youth Guidance to implement a randomized controlled trial to test the efficacy of Youth Guidance's Working on Womanhood program across two cohorts: Cohort 1, receiving programming during academic years 2017-18 and 2018-19, and Cohort 2, receiving programming during academic years 2018-19 and 2019-20. For Cohort 1, incoming 9th, 10th, and 11th grade female students in 10 Chicago Public Schools high schools (as of Fall 2017) will be screened for eligibility and randomized to either a treatment group that will be offered to receive WOW services over two academic years, or to a control group that will not be offered to receive WOW services over two academic years. For cohort 2, only incoming 9th graders (as of Fall 2018) will be randomized, in the same manner. Control group students will still be eligible to receive other status quo school and community supports. Outcomes of interest will be measured using administrative data and a comprehensive student survey.
WOW is a trauma-informed, in-school group counseling and clinical mentoring program developed by non-profit Youth Guidance. Informed by CBT, WOW helps girls challenge unhelpful thoughts and build self-esteem and self-efficacy to make positive and healthy decisions. WOW aims to reduce depression, anxiety, and PTSD symptoms, and improve academic and behavioral outcomes. WOW delivers a 26-lesson curriculum via weekly small-group counseling sessions during the school day. The curriculum is designed around five core values: self-awareness, emotional intelligence, healthy relationships, visionary goal setting, and leadership, and delivered by masters-level social workers and counselors. WOW counselors may also provide individual counseling and referrals to other services. The WOW program fills a critical gap in the existing set of programs available to these students, by providing services that cater to the unique needs of young women in our most under-resourced high schools.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
These youth will not receive Working on Womanhood (WOW) services during academic years 2017-18 and 2018-19 \[Cohort 1\] or 2018-19 and 2019-20 \[Cohort 2\] or after, and will not have contact with WOW clinicians. Control youth will be able to receive all other services available through their school as they normally would, such as access to the school counselor and after school programs.
These youth will receive Working on Womanhood (WOW) services during academic years 2017-18 and 2018-19 \[Cohort 1\] or 2018-19 and 2019-20 \[Cohort 2\]. These young women will participate in weekly group therapy and skill-building sessions, led by master's level clinicians, and will also receive individual support and therapy from their clinicians as-needed.
Behavioral: Working on Womanhood (WOW)
A trauma-informed group counseling and clinical mentoring intervention for young women
Change in depression assessment score
Score on self-reported depression screen, obtained from the Behavior Assessment System for Children, Third Edition (BASC-3) Self-Report of Personality (SRP)
Time frame: Up to 36 months
Change in post-traumatic stress disorder (PTSD) assessment score
Score on self-reported PTSD screen, obtained from the Child and Adolescent Trauma Screen (CATS)
Time frame: Up to 36 months
Change in anxiety assessment score
Score on self-reported anxiety screen, obtained from the BASC-3 SRP
Time frame: Up to 36 months
Change in high school graduation
On-time graduation rate, obtained from Chicago Public Schools (CPS) administrative database
Time frame: Up to 5 years
Change in absences
Rate and number of school absences, obtained from CPS administrative database
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in index of CPS schooling outcomes
Standardized index composed of GPA, number of course failures, attendance rate, and number of in-school and out-of-school suspensions, obtained from CPS administrative database
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in student misconduct
Number of in-school and out-of-school suspensions, obtained from CPS administrative database
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in course failures
Rate and number of courses failed, obtained from CPS administrative database
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in overall arrests
Number of total arrests, obtained from Chicago Police Department (CPD) and Illinois State Police (ISP) administrative databases
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in violent crime arrests
Number of arrests for violent crimes, obtained from CPD and ISP administrative databases
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in other arrests (property, drug, and other)
Number of non-violent crime arrests, including property crimes, drug crimes, and other crimes, obtained from CPD and ISP administrative databases
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in pregnancy/childbirth rate
Self-reported survey measures, obtained from representative student survey; Childbirth data, obtained from the Chicago and Illinois Dept. of Public Health
Time frame: 1-year, 2-year, 3-year, 4-year, 5-year
Change in sexual health and behaviors
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in substance use
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in school attitudes and engagement
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in family cohesion
Measures adapted from the Family Environment Scale (relationships section), obtained from representative student survey
Time frame: Up to 36 months
Change in self-esteem (self-reliance, sense of inadequacy)
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in emotional regulation
Score on the Difficulties in Emotion Regulation Scale - Short Form (DERS-SF), obtained from representative student survey
Time frame: Up to 36 months
Change in decision-making (self-efficacy, future orientation)
Score on the ZIMBARDO time perspective survey, Life Orientation Test - Revised (LOT-R), and other measures, obtained from representative student survey
Time frame: Up to 36 months
Change in peer aggression
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in somatization
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in attention problems (hyperactivity)
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in interpersonal relationships
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in locus of control and anger management
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in empowerment
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in self-concept
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in social supports
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Change in perception of racial / cultural identity
Self-reported survey measures, obtained from representative student survey
Time frame: Up to 36 months
Plan to share: No
No publications or documents are linked to this record.
Ran from Oct 2017 to primary completion in Nov 2021, 49 months.
Of 3,836 non-industry interventional studies with no phase under Anxiety Disorders, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 28. This study's 49 months is above that.
Counting every sponsor, half of 3,938 studies reached it within 12 months; a quarter within 5 and three quarters within 28.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.
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