ClinicalTrials.gg
CompletedNCT03322228Updated Nov 24, 2020

Music Therapy Intervention to Reduce Caregiver Distress at the End of Life

An interventional study of Music Therapy in Quality of Life, Stress and Anxiety, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-11-24.

Primary conditionDepressionRegistry: Anxiety DisordersReclassifiedWhy we changed it
Registry
Anxiety Disorders — the first condition term the registry derived for this study.
ClinicalTrials.gg
Depression
Why
  1. The registry often attaches Anxiety Disorders to studies about something else, and this study's title and listed conditions do not name it.
  2. The study's listed conditions name Depression.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Mayo Clinic · Not applicable, Interventional, and Supportive care

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Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 32 studies in Depression by Mayo Clinic — 4 open to participants now, 4 under way, none of them phase 3. Depression · Mayo Clinic.

Enrollment
20th of 28
20 · median 39
Started
2017
with 2 others
No phase
23 of 32
4 open now
Registered
21st of 32
by date

Among the 32 studies in Depression by Mayo Clinic, this one is the 20th largest by enrollment of the 28 interventional ones that give a count, is one of 3 that started in 2017, is one of 23 with no phase, and was the 21st registered.

Depression

8,582 studies on the registry are indexed under Depression; 1,723 are open to participants now.

Browse Depression studies →

Open to participants now

4 of the 32 studies in Depression by Mayo Clinic are open now, in 1 country. Recruiting first, the newest first:

By country, each count listing its studies:

All 4 open studies →

Where they have run

Who these studies take

Of the 1,089 Depression studies recruiting now, 470 (43%) set no upper age limit and 519 (48%) stop at 75 or younger; 203 take children under 18; 311 take healthy volunteers.

This study: 18 Years and older · all sexes · no healthy volunteers.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 32 studies in Depression by Mayo Clinic, or all of them as a file.
02

Study summary

This is a study to assess the feasibility and acceptability of implementing a music therapy intervention for caregivers of hospitalized patients who are referred to inpatient hospice.

Read the detailed description

Caregivers are at high risk for stress, poor quality of life (QOL), and burnout. As a patient nears death, common themes for caregivers include anxiety and emotional distress from impending death, anticipatory grief, and acceptance of loss, which negatively impact the caregiver QOL. Investigators propose to conduct a pilot project to investigate music therapy impact on caregiver distress for caregivers of imminently dying hospitalized patients referred to hospice. Upon enrollment, caregivers will be provided a music therapy intervention with legacy-building components, and will be asked to complete 3 brief questionnaires on distress and quality of life before and after the music therapy to assess their response to the intervention. The overall aim is to reduce caregiver distress and optimize QOL.

03

Conditions studied

  • Quality of Life
  • Stress
  • Anxiety
  • Depression

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Keywords

  • Hospice
  • Palliative Care
  • Integrative Medicine
  • Music Therapy
  • Inpatient
  • Caregiver
04

In context

Depression Reclassified

8,582 studies on the registry are indexed under Depression; 1,723 are open to participants now.

This study's enrollment of 20 is below the median of 81 across 7,066 interventional studies indexed under Depression.

Browse Depression studies →

Lead sponsor

Mayo Clinic is the lead sponsor of 3,270 studies on the registry; 672 are open to participants now.

Of its 452 completed or terminated interventional studies of FDA-regulated products, 321 (71%) have results posted.

Compared within Depression, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Anxiety Disorders. The counts are of registry records indexed under each term, refreshed daily. How we classify →

05

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Age > 18 years
  2. Self-identified caregiver
  3. English-speaking

Exclusion criteria

Exclusion Criteria:

  1. Unable to provide consent
06

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Music Therapy

    1 music therapy session, lasting approximately 45 min-1 hr

    Other: Music Therapy

Interventions

  • OtherMusic Therapy

    Music therapy is tailored to subject preference. Examples are active music-making, supportive listening, and includes opportunities for legacy building to decrease caregiver distress and promote self-care.

07

What researchers measure

Primary outcomes

  1. Pearlin role overload measure (ROM)

    4-item self-administered measure of caregiver stress

    Time frame: Baseline to 6 months

Secondary outcomes

  1. Linear Analogue Self-Assessment (LASA)

    10-item self-report of general measures of quality of life (QOL)

    Time frame: Baseline to 6 months

  2. Patient Health Questionnaire for Depression and Anxiety (PHQ-4)

    4-item self-administered screening tool that combined two validated two-item screeners for depression and anxiety

    Time frame: Baseline to 6 months

  3. Music Therapy Program Survey

    Survey to assess satisfaction regarding the therapy service provided

    Time frame: Up to 72 hours after intervention

08

Study locations

1 site
  • Mayo Clinic
    Rochester, Minnesota 55905, United States
09

References and documents

Individual participant data

Plan to share: No

10

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Oct 2017 to primary completion in Aug 2020, 34 months.

Of 3,471 non-industry interventional studies with no phase under Depression, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's 34 months is above that.

Counting every sponsor, half of 3,569 studies reached it within 21 months; a quarter within 9 and three quarters within 41.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 13, 2017
First posted
Oct 26, 2017
StartActual
Oct 5, 2017
Primary completionActual
Aug 31, 2020
CompletionActual
Aug 31, 2020
Last update
Nov 24, 2020
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Nov 24, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
11

Registry details

Key details

Study ID
NCT03322228
Lead sponsor
Mayo Clinic
Responsible party
Maria I. Lapid, M.D. (M.D., Mayo Clinic) — Principal investigator
First posted
Oct 26, 2017
Start date
Oct 5, 2017
Primary completion
Aug 31, 2020
Completion
Aug 31, 2020
Last update
Nov 24, 2020

Study contacts

Maria Lapid, MD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.

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