An interventional study of Enamel matrix derivative proteins and Open Flap debridement in Generalized Aggressive Periodontitis, sponsored by Universidade Estadual Paulista Júlio de Mesquita Filho. Completed at 1 site in Brazil. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-06-05.
Sponsored by Universidade Estadual Paulista Júlio de Mesquita Filho · Not applicable, Interventional, and Treatment
The aim of the present study is to evaluate the clinical response of proximal furcations treated with enamel matrix derivative proteins (EMD).
Proximal class-II furcation represents a challeng to periodontal therapy. Studies show that the ultrasonic non-surgical therapy doesn't work in these defects and the guided tissue regeneration therapy with membranes also demonstrates an unpredictable improvement. Therefore, enamel matrix derivative proteins (EMD) have been proposed as a periodontal regenerative procedure due to their fundamental role in cementum development.
63 studies on the registry are indexed under Aggressive Periodontitis; 5 are open to participants now.
This study's enrollment of 34 is close to the median of 34 across 41 interventional studies indexed under Aggressive Periodontitis.
Browse Aggressive Periodontitis studies →Universidade Estadual Paulista Júlio de Mesquita Filho is the lead sponsor of 82 studies on the registry; 9 are open to participants now.
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The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Open flap debridement to enamel matrix derivative application in proximal class-II furcation.
Procedure: Enamel matrix derivative proteins · Procedure: Open Flap debridement
Open flap debridement in proximal class-II furcation.
Procedure: Open Flap debridement
Open flap debridement to enamel matrix derivative to treat proximal furcation involvements.
Also known as: Surgical therapy
Open flap debridement will be performed to decontaminate the proximal furcation involvements.
Also known as: Surgical therapy
Horizontal clinical attachment level
horizontal component of the defect
Time frame: 1 year
Plan to share: Undecided — Undecided.
This study is completed, as verified in Jun 2019. You cannot join it, but the record below documents what was studied.
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Universidade Estadual Paulista Júlio de Mesquita Filho