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CompletedNCT03306225Updated Feb 5, 2020

Characterization of Endocarditis to Streptococci and Impact of the CMI on the Future of the Patients

An observational study in Endocarditis, Bacterial, sponsored by Fondation Hôpital Saint-Joseph. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-02-05.

Sponsored by Fondation Hôpital Saint-Joseph · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
414
Ages
18 Years and older
Sex
All
01

Study summary

The infectious endocarditis is a grave infection the incidence of which is at present esteemed at 30-100 episodes by million inhabitants a year.

This infection is marked with a heavy morbi-mortality.Preliminary studies seem to show an abnormally high death rate at the patients presenting an infectious endocarditis to streptococci with an inhibitive minimal concentration raised to the amoxicilline. The aim of the study is to describe the epidemiology and the clinical presentations of the patients presenting an endocarditis to streptococci

02

Conditions studied

  • Endocarditis, Bacterial
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In context

Endocarditis, Bacterial

22 studies on the registry are indexed under Endocarditis, Bacterial; 9 are open to participants now.

This study's enrollment of 414 is below the median of 588 across 10 observational studies indexed under Endocarditis, Bacterial.

Browse Endocarditis, Bacterial studies →

Lead sponsor

Fondation Hôpital Saint-Joseph is the lead sponsor of 346 studies on the registry; 51 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

all patient diagnostised for endocarditis between 2010 and 2015

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • age > 18 years
  • endocartitis with steptococci with Duke's criteria

Exclusion criteria

Exclusion Criteria:

  • age \< 18 years
  • suspiscious endocarditis without Duke's criteria
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
414 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Evaluation of factors associated to the mortality in the patients presenting an endocarditis to streptococci.

    Time frame: an average of one year

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Study locations

1 site
  • Groupe Hospitalier Paris Saint Joseph
    Paris, Ile-de-France 75014, France
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 5, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT03306225
Responsible party
Sponsor
First posted
Oct 10, 2017
Start date
Jul 8, 2016
Primary completion
Dec 31, 2018
Completion
Dec 31, 2019
Last update
Feb 5, 2020

Study contacts

PILMIS P Benoit, MD
principal investigator · Fondation Hôpital Saint-Joseph

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2020. You cannot join it, but the record below documents what was studied.

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Discussion

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