An interventional study of Mindfulness Meditation in Chronic Pain and Depression, Anxiety, sponsored by York University. Completed at 1 site in Canada. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-06-09.
Sponsored by York University · Not applicable, Interventional, and Treatment
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Among 202 studies in Chronic Pain with a site in Canada — 52 open to participants now, 63 under way, 3 of them phase 3. Chronic Pain · Canada.
Among the 202 studies in Chronic Pain with a site in Canada, this one is the 2nd largest by enrollment of the 162 interventional ones that give a count, is one of 14 that started in 2017, is one of 116 with no phase, and was the 66th registered.
3,227 studies on the registry are indexed under Chronic Pain; 728 are open to participants now.
Browse Chronic Pain studies →52 of the 202 studies in Chronic Pain with a site in Canada are open now. Recruiting first, the newest first:
Ottawa Hospital Research Institute · Sites in Canada
Ages 18+
Laval University · Sites in Canada
Ages 65+
University Health Network, Toronto · Sites in Canada
Ages 18–80
University Health Network, Toronto · Sites in Canada
Ages 18–65
University of Manitoba · Sites in Canada
Ages 18+
A study can be open while its sites in Canada have not opened yet or have stopped. Only those recruiting at a site in Canada →
Of the 486 Chronic Pain studies recruiting now, 239 (49%) set no upper age limit and 173 (36%) stop at 75 or younger; 43 take children under 18; 64 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
202 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 8 · Phase 2 22 · Phase 3 14 · Phase 4 8
First in 2004; this study’s year is marked. 14 started in 2017.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 2,016 is above the median of 60 across 2,387 interventional studies indexed under Chronic Pain.
Median enrollment 49 across the 162 interventional studies, 138 across the 40 observational. Of the 107 that completed or were terminated, 14 (13%) have results posted.
This tab as a report to print or save as PDF → With an account.
16 of 202 have an industry lead sponsor. The 10 most frequent:
York University is the lead sponsor of 51 studies on the registry; 12 are open to participants now.
York University has 3 studies filed under Chronic Pain — fewer than ten, so there is no comparison to draw.
16 of the studies in Chronic Pain with a site in Canada that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT05306899Phase 3University Health Network, TorontoMulti-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches | 2027-02-01 |
| NCT07137845Université de SherbrookeVirtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans | 2026-12 |
| NCT06123715University Health Network, TorontoPerioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty | 2026-12-31 |
| NCT04939623University of CalgaryNovel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal | 2026-12-31 |
| NCT03675386University Health Network, TorontoReducing Opioid Use for Chronic Pain Patients Following Surgery | 2026-12-31 |
Add all 16 to your calendar (.ics) → With an account.
Among the 202 studies in Chronic Pain with a site in Canada, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The aim of the present study is to evaluate the psychophysiological effects of a smart phone based mindfulness meditation app (MMA) for individuals with clinically significant symptoms of major depression and/or anxiety, or symptoms of chronic pain. Specifically, the study aims to examine parasympathetic tone using HRV (primary outcome), mind-wandering and present awareness, mood symptoms, and breath focus in groups of participants who self-report clinically significant symptoms of depression and/or anxiety (DA), chronic pain symptoms (CP), as well as control participants who do not meet our criteria for either (Controls (C). All study groups will be randomized to a mindfulness meditation app (MMA+) condition or a mindfulness meditation condition without the app (MMA-) after a brief stress-induction procedure.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Participants randomized to this arm will use a smartphone app to practice mindfulness meditation for 12 minutes.
Behavioral: Mindfulness Meditation
Participants randomized to this arm will not use a smartphone app, but will receive instructions to practice mindfulness meditation for 12 minutes.
Behavioral: Mindfulness Meditation
A meditative practice involving paying attention to present moment experiences and focusing on breathing sensations.
Heart Rate Variability
A stress biomarker derived from heart rate recordings that reflects parasympathetic control of cardiac output
Time frame: 22 minutes
Plan to share: No
Ran from Nov 2017 to primary completion in May 2020, 29 months.
Of 1,295 non-industry interventional studies with no phase under Chronic Pain, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 39. This study's 29 months is above that.
Counting every sponsor, half of 1,378 studies reached it within 20 months; a quarter within 9 and three quarters within 38.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jun 2022. You cannot join it, but the record below documents what was studied.
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York University