CClinicalTrials.gg
CompletedNCT03259100Updated Aug 24, 2017

Temperature and Mortality

An observational study in Cardiovascular Diseases, sponsored by Chinese Academy of Sciences. Completed. Open to participants aged 35 Years and older. Per ClinicalTrials.gov, last updated 2017-08-24.

Sponsored by Chinese Academy of Sciences · Observational

Study type
Observational
Model
Ecologic or community
Time perspective
Retrospective
Enrollment
17,000,000
Ages
35 Years and older
Sex
All
01

Study summary

The investigators evaluated the spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature (Ta) , and then used this relationship to model future temporal trends in mortality from CVD and stroke till the end of century (2099) using different warming scenarios across the mainland USA.

Read the detailed description

the investigators used data on mortality rate (per 100,000 individuals) for CVD and stroke (between 2011 and 2013, age>35years) from the publicly available Centers for disease prevention and control (CDC) web site (www.cdc.gov). CVD mortality was defined as the number of deaths per 100,000 personyears due to circulatory causes (International Statistical Classification of Diseases, Tenth Revision, codes I00-I99).Oak Ridge National laboratory was the source of the ambient temperature data (http://www.daac.ornl.gov: files B01, B02 and C07).The investigators obtained data on prevalence of HTN (HTN was defined as systolic blood pressure (BP) of at least 140 mm Hg, self-reported use of antihypertensive treatment, or both) from county health rankings and roadmaps organisation (www.countyhealthrankings.org), which were estimated based on National Health and Nutrition Examination Survey in five two-year waves from 1999-2008 including 26,349 adults aged 30 years and older and from the Behavioral Risk Factor Surveillance System (BRFSS) from 1997-2009 including 1,283,722 adults aged 30 years and older.

02

Conditions studied

  • Cardiovascular Diseases
03

Who can participate

Ages eligible
35 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

We used data on mortality rate (per 100,000 individuals) for CVD and stroke (between 2011 and 2013, age>35years) from the publicly available Centers for disease prevention and control (CDC) web site (www.cdc.gov).

Inclusion criteria

  1. age>35 years

Exclusion criteria

Exclusion Criteria:

None

04

Study design

Observational model
Ecologic or community
Time perspective
Retrospective
Enrollment
17,000,000 participants (actual)
Patient registry
No

Interventions

  • Otherall the data collection have done by CDC.

    In this study there was no intervention, just simple data collection via CDC.

05

What researchers measure

Primary outcomes

  1. spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature

    spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature

    Time frame: 2011-2013

06

Study locations

No study locations are listed for this record.

07

References and documents

Publications

  • Mazidi M, Speakman JR. Ambient particulate air pollution (PM2.5) is associated with the ratio of type 2 diabetes to obesity. Sci Rep. 2017 Aug 22;7(1):9144. doi: 10.1038/s41598-017-08287-1. PubMed 28831041 ↗
  • Mazidi M, Speakman JR. Higher densities of fast-food and full-service restaurants are not associated with obesity prevalence. Am J Clin Nutr. 2017 Aug;106(2):603-613. doi: 10.3945/ajcn.116.151407. Epub 2017 May 31. PubMed 28566310 ↗
  • Speakman JR, Heidari-Bakavoli S. Type 2 diabetes, but not obesity, prevalence is positively associated with ambient temperature. Sci Rep. 2016 Aug 1;6:30409. doi: 10.1038/srep30409. PubMed 27477955 ↗

Related links

Individual participant data

Plan to share: Yes — all of our data are in public available, www.CDC.gov

Supporting information: Study protocol, Icf, Analytic code

08

Registry details

Key details

Study ID
NCT03259100
Lead sponsor
Chinese Academy of Sciences
Responsible party
John Speakman (Principal Investigator, Chinese Academy of Sciences) — Principal investigator
First posted
Aug 23, 2017
Start date
Jan 1, 2011
Primary completion
Jan 1, 2012
Completion
Feb 1, 2013
Last update
Aug 24, 2017

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2017. You cannot join it, but the record below documents what was studied.

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