An observational study in Thoracic Surgery and Ventilation Therapy; Complications, sponsored by Fundación para la Investigación del Hospital Clínico de Valencia. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-03-07.
Sponsored by Fundación para la Investigación del Hospital Clínico de Valencia · Observational
During thoracic surgical procedures, while ventilating with a protective tidal volume, an open lung approach consisting of a recruitment maneuver followed by an individualized positive end-expiratory pressure (PEEP) titrated to best respiratory system compliance (Open-lung PEEP, OL-PEEP) would decrease driving pressure. To test this hypothesis, we performed a multicenter observational study in 17 Spanish teaching hospitals of patients undergoing one lung ventilation (OLV). In addition, we analyzed the association between the driving pressure and the prevalence of postoperative pulmonary complications (PPCs), and finally the association between the individualized PEEP and relevant patient preoperative or intraoperative variables.
386 studies on the registry are indexed under Aortic Dissection; 117 are open to participants now.
This study's enrollment of 690 is above the median of 183 across 180 observational studies indexed under Aortic Dissection.
Browse Aortic Dissection studies →Fundación para la Investigación del Hospital Clínico de Valencia is the lead sponsor of 70 studies on the registry; 17 are open to participants now.
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Patients undergoing one lung ventilation during thoracic surgical procedures
Exclusion Criteria:
Postoperative pulmonary complications
Atelectasis, acute respiratory failure, ARDS, pneumonia, reintubation, empyema, bronchospasm, pneumothorax, pneumonitis, bronchopleural fistula
Time frame: Postoperative. One week
Descriptive analysis of the open lung PEEP
Open lung PEEP is the PEEP of best dynamic respiratory system compliance during a PEEP titration trial
Time frame: intraoperative
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.
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Fundación para la Investigación del Hospital Clínico de Valencia