An observational study in Postoperative Delirium, sponsored by Zhongda Hospital. Completed at 1 site in China. Open to participants aged 65 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-12-27.
Sponsored by Zhongda Hospital · Observational
This study evaluated the predictive value of β2-microspheres for postoperative delirium (POD) in the elderly after orthopedic surgery. For this purpose, the levels of β2-microspheres in plasma and cerebrospinal fluid were compared between the POD and non-POD groups.
In this study, plasma and cerebrospinal fluid of the patients were collected to detect the levels of β2-microspheres before operation. Also, the patients were interviewed one day before the surgery and on postoperative days 1-3 by the Confusion Assessment Method and then divided them into POD and non-POD groups. The aim of the present study was to assess whether higher levels of β2-microspheres could predict the occurrence of POD.
1,057 studies on the registry are indexed under Delirium; 238 are open to participants now.
This study's enrollment of 184 is close to the median of 200 across 418 observational studies indexed under Delirium.
Browse Delirium studies →Zhongda Hospital is the lead sponsor of 101 studies on the registry; 40 are open to participants now.
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Patients aged ≥65 years undergoing orthopedic operations under spinal anesthesia were investigated.
Exclusion Criteria:
POD group refers to the patients who were diagnosed to be delirious by the Confusion Assessment Method.
Non-POD refered to the patients who did not become delirious by the Confusion Assessment Method.
The incidence of POD
The patients were interviewed one day before the surgery and on postoperative days 1-3 by the Confusion Assessment Method and then divided them into POD and non-POD groups.
Time frame: 4 days
The levels of β2-microspheres in plasma and cerebrospinal fluid
Before surgery, plasma and cerebrospinal fluid of the patients were collected to detect the levels of β2-microspheres.
Time frame: 1 day
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Dec 2018. You cannot join it, but the record below documents what was studied.
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Zhongda Hospital