An observational study in Autoimmune Diseases and Chronic Lymphocytic Thyroiditis, sponsored by Centre Hospitalier Universitaire, Amiens. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-04-14.
Sponsored by Centre Hospitalier Universitaire, Amiens · Observational
Autoimmune diseases represent a heterogeneous group of pathologies whose etiopathogenic mechanisms are most often unknown. Autoimmune diseases are the leading cause of morbidity and mortality in young women and autoimmune thyroid diseases are the most common.
Viral infections are the main environmental factors suspected of triggering autoimmune diseases. Several viruses are certainly involved, all of which are possibly capable of triggering an autoimmune response. However, the precise identification of the viruses involved remains to be established.
It has been shown for the first time by the 2005 PHRC that enteroviral RNA is present in perioperative specimens of thyroid tissue. However, this case-control study did not show any difference between the thyroid group and the group other thyroid pathologies It has been recently published that Parvovirus is possibly involved in thyroiditis: the parvoviral genome is present in the thyroid tissue of Hashimoto thyroiditis operated and more precisely is present within the thyrocytes itself.
53 studies on the registry are indexed under Hashimoto Disease; 13 are open to participants now.
This study's enrollment of 64 is below the median of 112 across 22 observational studies indexed under Hashimoto Disease.
Browse Hashimoto Disease studies →Centre Hospitalier Universitaire, Amiens is the lead sponsor of 586 studies on the registry; 185 are open to participants now.
Compared within Hashimoto Disease, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Autoimmune Diseases. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Patients were recruited after PHRC 2005. Written information for the extension of the study will be sent with a copy of the summary of the scientific publication on Enterovirus (PHRC 2005).
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Exclusion Criteria:
Other: Comparison of the prevalences of the parvovirus genome
Other: Comparison of the prevalences of the parvovirus genome
Comparison of the prevalences of the parvovirus genome between cases and controls and then of other viruses according to the results of parvoviruses and data from the literature
Analysis of the viral genome by PCR carried out in the Virology department, Analysis of the presence of capsid protein
Time frame: 1 day
Ran from Jan 2012 to primary completion in Jan 2015, 36 months.
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This study is completed, as verified in Apr 2017. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire, Amiens →