An observational study in Blood Pressure, Low, sponsored by Kaohsiung Medical University Chung-Ho Memorial Hospital. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-06-21.
Sponsored by Kaohsiung Medical University Chung-Ho Memorial Hospital · Observational
Orthognathic surgery, one kind of Oro-maxillofacial surgery, is a complicate surgery that undergoes several hours with nasotracheal intubation general anesthesia. To limit blood loss during operation, the patients are often under intentional hypotension. However, the intentional hypotension may confuse with hypovolemic induced low blood pressure. The hypothesis is using flotrac (to measure stroke volume variation) to keep the patients hemodynamics stable under Tridil and propofol infusion and avoid over-infusion of crystalloid or colloid and prevent hypovolemia induced postoperative nausea and vomiting.
Orthognathic surgery, one kind of oro-maxillofacial surgery, is a complicated surgery that undergoes several hours with nasotracheal intubation general anesthesia. Patients without premedication undergo orthognathic surgery with nasotracheal intubation general anesthesia.
Patients without premedications Monitoring of patients with entropy for consciousness, ECG, with noninvasive BP and invasive blood pressure through redial artery, train-of-four monitor, target controlled infusion of propofol, infusion Tridil, and sevoflurane for mainly anesthesia maintenance. Ventilator setting as volume control (8-12ml/kg), frequency respiratory rate (8-12/min), I/E ratio: 1/2, positive end expiratory pressure: 4 mmHg, Fraction inspiratory O2: 60%.
To maintain the MAP >60-55 mmHg, urine output 0.5-1ml/kg, and body core temperature > 36 Celsius degree.
Closely observation of patients postoperatively for adverse events or complications.
1,003 studies on the registry are indexed under Hypotension; 173 are open to participants now.
This study's enrollment of 60 is below the median of 84 across 294 observational studies indexed under Hypotension.
Browse Hypotension studies →Kaohsiung Medical University Chung-Ho Memorial Hospital is the lead sponsor of 281 studies on the registry; 57 are open to participants now.
Counted across the registry records on this site, refreshed daily.
patients who need to operate for abnormal face or abnormal teeth biting
Exclusion Criteria:
using medications to maintain low stable blood pressure
blood loss measurement
to maintain low blood pressure (MAP \> 55mmHg) to limit blood loss
Time frame: 10hrs
assessment of inappropriate fluid infusion
count the fluid given by stroke volume variation but fixed time administration
Time frame: 10hours
postoperative adverse events
adequate medications to maintain low stable BP to decrease tissue edematous change
Time frame: 2 days
Plan to share: No
This study is completed, as verified in Mar 2017. You cannot join it, but the record below documents what was studied.
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Kaohsiung Medical University Chung-Ho Memorial Hospital