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CompletedNCT03081403SENSISKINUpdated Feb 4, 2025

Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

An interventional study of Quantitative Sensory Testing in Sensitive Skin, sponsored by University Hospital, Brest. Completed at 1 site in France. Open to participants aged 20 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-02-04.

Sponsored by University Hospital, Brest · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
42
Allocation
Non-randomized
Ages
20 Years to 60 Years
Sex
All
01

Study summary

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin.

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Read the detailed description

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress...

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

02

Conditions studied

  • Sensitive Skin

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Keywords

  • Sensitive skin
  • Quantitative Sensory Testing
03

In context

Hypersensitivity

1,916 studies on the registry are indexed under Hypersensitivity; 265 are open to participants now.

This study's enrollment of 42 is below the median of 57 across 1,384 interventional studies indexed under Hypersensitivity.

Browse Hypersensitivity studies →

Lead sponsor

University Hospital, Brest is the lead sponsor of 594 studies on the registry; 135 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Age: between 20 and 60 years
  • Cooperating patient
  • Informed and written consent of the subject
  • Affiliated to the social security
  • For subjects with sensitive skin:

subjects with a score greater than 50 on the scale sensitive scale

  • To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion criteria

Exclusion Criteria:

  • Adults subject with legal protection
  • Subject in a social institution.
  • Subject with major cognitive or psychiatric disorders
  • Subject with pathological use of alcohol or consumption of another drug.
  • Subject with skin involvement of the back of the dominant hand or malformation.
  • Known sensitive neuropathy
  • Pregnant woman
  • Subject receiving medical treatment which may interfere with the results.
  • Subject with treatment in the back of the dominant hand.
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
42 participants (actual)

Study arms

  • Other
    Subjects with sensitive skin

    Subjects with a score greater than 50 on the sensitive scale

    Device: Quantitative Sensory Testing

  • Other
    Subjects without sensitive skin

    Subjects with result lower than 20 on the sensitive scale

    Device: Quantitative Sensory Testing

Interventions

  • DeviceQuantitative Sensory Testing

    Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.

06

What researchers measure

Primary outcomes

  1. Cutaneous perception threshold

    The cutaneous perception threshold of pain to heat.

    Time frame: 6 months

Secondary outcomes

  1. The cutaneous perception threshold of vibration

    The cutaneous perception threshold of pain to harm.

    Time frame: 6 months

  2. The cutaneous perception threshold of cold

    The cutaneous perception threshold of cold

    Time frame: 6 months

07

Study locations

1 site
  • CHRU de Brest
    Brest, 29200, France
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03081403
Lead sponsor
University Hospital, Brest
Responsible party
Sponsor
First posted
Mar 16, 2017
Start date
Apr 14, 2017
Primary completion
Sep 22, 2017
Completion
Oct 27, 2017
Last update
Feb 4, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.

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