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Not yet recruitingNCT07803627FLEXIMIX3Updated Sep 3, 2026

Changes in the Angle of Uterine Flexion as the Bladder Fills

An interventional study of Ultrasonography, Pelvic in Uterine Anteflexion, sponsored by University Hospital, Brest. Not yet recruiting at 1 site in France. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-03.

Sponsored by University Hospital, Brest · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
18 Years and older
Sex
Female
01

Study summary

The goal of this clinical trial is to evaluate how bladder filling affects the uterine flexion angle in adult nulliparous women with a uterine flexion angle \<90° when the bladder is empty.

The main questions it aims to answer are:

How does the uterine flexion angle change as bladder volume increases? What bladder volume is needed to obtain a uterine flexion angle >90°?

Participants will:

Drink 600 mL of water following a standardized protocol. Undergo repeated suprapubic ultrasound measurements of bladder volume and uterine flexion angle.

Remain under observation until urination or for a maximum of 4 hours. No comparison group is included in this study.

02

Conditions studied

  • Uterine Anteflexion

Keywords

  • Uterine anteflexion
  • Nulliparous women
  • Bladder filling
  • Ultrasound measurements
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Adult woman
  • Nulliparous
  • Registered with a social security scheme
  • Uterine flexion angle \< 90°, empty bladder

Exclusion criteria

Exclusion Criteria:

  • Pregnant woman
  • Woman wishing to become pregnant and currently trying to conceive
  • Primary amenorrhoea
  • Menopause
  • History of surgical termination of pregnancy
  • History of medical termination of pregnancy
  • History of hysterectomy
  • History of conisation
  • Absence of the uterus
  • Symptoms of urinary tract infection (gross haematuria, burning on urination, frequent urination)
  • Under legal guardianship (curatorship, trusteeship)
04

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Other
    Ultrasonography pelvic

    Repeated ultrasound measurements, alternating between volume and angle of flexion, immediately following a hydration protocol and then bladder emptying.

    Procedure: Ultrasonography, Pelvic

Interventions

  • ProcedureUltrasonography, Pelvic

    Repeated ultrasound measurements, alternating between volume and angle of flexion, immediately following a hydration protocol and then bladder emptying.

05

What researchers measure

Primary outcomes

  1. Uterine Flexion Angle Measured at Different Bladder Volumes in Nulliparous Women With an Anteverted Uterus and Baseline Uterine Flexion Angle <90°

    The relationship between bladder volume and the angle of uterine flexion, as determined from repeated ultrasound measurements in the participants.

    Time frame: 4 hours

06

Study locations

1 site
07

References and documents

Individual participant data

Plan to share: Yes — All collected data that underlie results in a publication

Supporting information: Study protocol

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07803627
Lead sponsor
University Hospital, Brest
Responsible party
Sponsor
First posted
Sep 3, 2026
Start date
Sep 15, 2026 (estimated)
Primary completion
Mar 15, 2027 (estimated)
Completion
Mar 15, 2027 (estimated)
Last update
Sep 3, 2026

Study contacts

Benoit CHIRON, MD
Contact
benoitchiron@yahoo.fr
02 98 40 19 21 ext. +33

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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