An interventional study of Space from Depression in Depression, sponsored by Silver Cloud Health. Completed at 2 sites in Colombia. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2018-09-10.
Sponsored by Silver Cloud Health · Not applicable, Interventional, and Treatment
Among 24 studies in Depression with a site in Colombia — 4 open to participants now, 5 under way, none of them phase 3. Depression · Colombia.
Among the 24 studies in Depression with a site in Colombia, this one is the 16th largest by enrollment of the 22 interventional ones, is the only one that started in 2016, is one of 14 with no phase, and was the 12th registered.
8,577 studies on the registry are indexed under Depression; 1,720 are open to participants now.
This study's enrollment of 127 is above the median of 81 across 7,063 interventional studies indexed under Depression.
Browse Depression studies →4 of the 24 studies in Depression with a site in Colombia are open now, in 1 country. Each count lists the studies.
Of the 1,088 Depression studies recruiting now, 469 (43%) set no upper age limit and 519 (48%) stop at 75 or younger; 203 take children under 18; 310 take healthy volunteers.
This study: 18 Years to 80 Years · all sexes · no healthy volunteers.
The full table on the hub →24 studies; the count open now beside each. This study's row is marked.
First in 1995; this study’s year is marked. 1 started in 2016.
Median enrollment 230 across the 22 interventional studies, 2,512 across the 2 observational. Of the 17 that completed or were terminated, 10 (59%) have results posted.
9 of 24 have an industry lead sponsor. The 10 most frequent:
Silver Cloud Health is the lead sponsor of 7 studies on the registry; none are open to participants now.
Silver Cloud Health has 7 studies filed under Depression — fewer than ten, so there is no comparison to draw.
2 of the studies in Depression with a site in Colombia that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06651554Brown UniversityTechnology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia | 2026-12-15 |
| NCT07633626Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento AnguloVortioxetine for Cognitive Function in ALK-positive NSCLC Treated With Lorlatinib | 2027-03-10 |
Among the 24 studies in Depression with a site in Colombia, from their registry updates:
Nothing recorded among them since 2026-09-25.
The study seeks to evaluate the efficacy of a culturally adapted internet-delivered treatment for depression in Colombia. The research involves two studies: (a) the cultural adaptation of the Space from Depression cognitive-behavioural internet-delivered programme, and (b) the implementation of the culturally adapted intervention using a randomised controlled trial methodology. The study will be a first contribution of a culturally adapted low-intensity internet-delivered intervention with Latin Americans.
Depression is the principal cause of disability in the world. High rates of prevalence of depression in general populations and college students have been found worldwide and in various cultural groups. For instance, a 12-month prevalence rate has been estimated in the U.S. at 9.5% and in Europe at 8.5% of the population. In Colombia, 12-month prevalence is between 6.2% and 12.1%. The Colombian National Mental Health Survey has estimated point prevalence of mild to moderate depressive symptoms at 15.6% and severe depressive symptoms at 4.2% of adults. On the other hand, there are significant barriers for accessing mental health services in Colombia. About 50% of the population does not have access to health services, while the majority of the population with mental health problems do not have adequate mental health insurance coverage.
Although low-intensity interventions for depression have been developed in western high-income countries and these interventions therefore have been influenced by their specific cultural context (for example, Ireland, UK, Australia), it is important to consider how cultural context may impact on the adaptation for use in LMICs such as Colombia. The authors argue that cultural aspects need to be taken into consideration when translating and adapting interventions to help guarantee similar results to what have been achieved in high-income countries.
General method Aims and Hypothesis: We aim to assess the efficacy of a culturally adapted cognitive behavioural internet-delivered treatment for college students with depressive symptoms in Colombia. In line with other studies in high-income countries (HICs), and using an already established intervention, we hypothesise that the culturally adapted Space from Depression programme will be efficacious, with significant changes within the treatment group and differences post-treatment between the active treatment and the waiting list control group.
The study is a mixed method approach utilising in study 1, quantitative and qualitative methods to assist in the cultural adaptation of the Space from Depression intervention and in study 2 a randomised control design to examine the efficacy of the culturally-adapted intervention.
Procedure The programme Space from Depression will be culturally adapted for a Colombian population using cultural sensitivity and ecological validity frameworks, including principles from cross-cultural assessment research. (Study 1). Once the programme is culturally adapted, it will be tested using a randomised controlled trial methodology (Study 2).
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
SilverCloud Health is a leading provider of online therapeutic solutions to support and promote positive behavior change and mental wellness. SilverCloud delivers interventions depression. The treatment includes self-monitoring, behavioural activation, cognitive restructuring, and challenging core beliefs. All modules have the same structure and format, which consist of quizzes, videos, educational content, activities with homework suggestions and a module review page. Also, users have a supporter, who will give feedback asynchronously (D Richards et al., 2015). Research on the SilverCloud interventions has yielded significant clinical outcomes (D Richards et al., 2015).
Behavioral: Space from Depression
Waiting list
Space from Depression programme (Yo puedo sentirme Bien -Spanish version) consists of seven modules of cognitive-behavioural therapy. The treatment includes self-monitoring, behavioural activation, cognitive restructuring, and challenging core beliefs. All modules have the same structure and format, which consist of quizzes, videos, educational content, activities with homework suggestions and a module review page.
Also known as: Yo puedo sentirme bien
Patient Health Questionnaire -9
depression symptoms
Time frame: 6 months
Generalised Anxiety Disorder 7
anxiety symptoms
Time frame: 6 months
Satisfaction with Treatment Questionnaire
Patient satisfaction
Time frame: 2 months
Helpful Aspects of Therapy Questionnaire
Significant events
Time frame: weekly for 7 weeks
Plan to share: No
Ran from Aug 2016 to primary completion in Mar 2018, 18 months.
Of 3,468 non-industry interventional studies with no phase under Depression, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's 18 months is below that.
Counting every sponsor, half of 3,566 studies reached it within 21 months; a quarter within 9 and three quarters within 41.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2018. You cannot join it, but the record below documents what was studied.
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