An interventional study of retrograde flow and oxygen in Chronic Obstructive Pulmonary Disease, sponsored by University of Split, School of Medicine. Completed. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-12-28.
Sponsored by University of Split, School of Medicine · Not applicable, Interventional, and Basic science
The aim of the study is to determine if increased retrograde shear would further deteriorate the already impaired vascular function in severe COPD patients.
3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.
This study's enrollment of 27 is below the median of 72 across 2,118 interventional studies indexed under Lung Diseases.
Browse Lung Diseases studies →University of Split, School of Medicine is the lead sponsor of 49 studies on the registry; 16 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Retrograde flow was induced in control subjects.
Other: retrograde flow
Retrograde flow was induced in hypoxemic COPD patients.
Other: retrograde flow
Retrograde flow was induced in COPD patients with normalized arterial oxygen saturation.
Other: retrograde flow · Other: oxygen
COPD patients with normalized arterial oxygen saturation.
Other: oxygen
Two pneumatic cuffs were placed on the experimental arm, one on the lower forearm, and the other on the upper arm. Two cuffs were simultaneously inflated for 20 minutes. The distal cuff was inflated to 75 mm Hg and the proximal cuff was inflated to 40 mm Hg. The contralateral (control) arm was cuff free during this intervention.
Supplemental 100% oxygen administered through a nasal cannula.
Change from Baseline Brachial Artery Diameter at 10, 20 and 25 minutes
Time frame: 0,10, 20 and 25 minutes
Change from Baseline Microparticle Count at 20 minutes
Time frame: 0 and 20 minutes
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Dec 2016. You cannot join it, but the record below documents what was studied.
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University of Split, School of Medicine