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CompletedNCT02996786Updated Apr 20, 2018

Effects of Danggui Buxue Tang on Blood Biochemical Parameters in Male Recreational Runners

An interventional study of Danggui Buxue Tang and Placebo in Sports Anemia, Inflammation and Oxidative Stress, sponsored by Kaohsiung Medical University Chung-Ho Memorial Hospital. Completed at 1 site in Taiwan. Open to male participants aged 20 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-04-20.

Sponsored by Kaohsiung Medical University Chung-Ho Memorial Hospital · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
39
Allocation
Randomized
Ages
20 Years to 30 Years
Sex
Male
01

Study summary

The aim of this study is to examine the beneficial effects of Danggui Buxue Tang on blood biochemical parameters in male recreational runners.

Read the detailed description
  1. Male recreational runners would be recruited by community websites or email. After completely introducing the study, the participants would be requested to sign informed consent.
  2. The participants would perform maximal oxygen consumption test prior to the supplementation. The participants would be supplemented with either Danggui Buxue Tang or placebo for a week before performing the 13-km run. A total of 4 times blood collection (before supplementation, immediate after running, 1 day and 3 days after running) would be performed for evaluating the effect of Danggui Buxue Tang on blood biochemical parameters.
02

Conditions studied

  • Sports Anemia
  • Inflammation
  • Oxidative Stress
  • Iron Deficiency
  • Hemolysis
  • Fatigue
03

In context

Iron Deficiencies

772 studies on the registry are indexed under Iron Deficiencies; 115 are open to participants now.

This study's enrollment of 39 is below the median of 100 across 592 interventional studies indexed under Iron Deficiencies.

Browse Iron Deficiencies studies →

Lead sponsor

Kaohsiung Medical University Chung-Ho Memorial Hospital is the lead sponsor of 281 studies on the registry; 57 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 30 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • The participants should have the experience finishing 10-km run but without the experience of attending a marathon run.

Exclusion criteria

Exclusion Criteria:

  • Participants suffering from anemia (Hb \<13 g/dL), taking usual supplements, medication, alcohol or not feeling comfortable.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
39 participants (actual)

Study arms

  • Experimental
    Danggui Buxue Tang group

    Danggui Buxue Tang group receive orally supplementation of 7.5 g/day of Danggui Buxue Tang for 10 days

    Dietary Supplement: Danggui Buxue Tang

  • Placebo comparator
    Placebo group

    Placebo group receive orally supplementation of 7.5 g/day of placebo for 10 days

    Other: Placebo

Interventions

  • Dietary supplementDanggui Buxue Tang

    Danggui Buxue Tang purchased from Kaiser Pharmaceutical

  • OtherPlacebo

    Consisting of corn starch and carboxymethyl cellulose

06

What researchers measure

Primary outcomes

  1. Hematological parameters

    Complete blood counts and serum haptoglobin and erythropoietin

    Time frame: Through study completion, an average of 1 year

  2. Iron status

    Serum iron, ferritin, transferrin and hepcidin

    Time frame: Through study completion, an average of 1 year

  3. Oxidative stress

    Thiobarbituric acid reactive substances, superoxide dismutase, catalase, and glutathione peroxidase

    Time frame: Through study completion, an average of 1 year

  4. Inflammatory response

    High-sensitivity c-reactive protein, Tumor necrosis factor-alpha, and interleukin-6

    Time frame: Through study completion, an average of 1 year

Secondary outcomes

  1. Running time

    The completion time for a 13-km run

    Time frame: Through study completion, an average of 1 year

07

Study locations

1 site
  • Kaohsiung Medical University
    Kaohsiung, 807, Taiwan
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 20, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02996786
Lead sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Responsible party
Sponsor
First posted
Dec 19, 2016
Start date
Oct 2016
Primary completion
Jul 2017
Completion
Jul 2017
Last update
Apr 20, 2018

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2016. You cannot join it, but the record below documents what was studied.

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