An observational study in Chorioamnionitis Affecting Fetus or Newborn, sponsored by Catholic University of the Sacred Heart. Completed. Per ClinicalTrials.gov, last updated 2016-12-19.
Sponsored by Catholic University of the Sacred Heart · Observational
Histologic chorioamnionitis (HCA) may lead to the fetal inflammatory response syndrome (FIRS) and increased levels of proinflammatory molecules.
Histologic chorioamnionitis (HCA) may lead to the fetal inflammatory response syndrome (FIRS). The aim of this pilot study was to evaluate S100A12, a marker of innate immune activation, in mothers with or without HCA and in their infants.
Concentrations of S100A12, Interleukin 6 (IL-6) and C-reactive protein (CRP) were evaluated in maternal, cord, and neonatal blood of very preterm infants. Histologic examinations of placentae and umbilical cords were performed.
39 studies on the registry are indexed under Chorioamnionitis; 9 are open to participants now.
This study's enrollment of 69 is below the median of 125 across 14 observational studies indexed under Chorioamnionitis.
Browse Chorioamnionitis studies →Catholic University of the Sacred Heart is the lead sponsor of 237 studies on the registry; 29 are open to participants now.
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Very Premature Mother-Neonate Pairs
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Preterm Birth
Exclusion Criteria:
Congenital Abnormalities
maternal chorioamnionitis
no maternal chorioamnionitis
S100A12 in Presence of Maternal Chorioamnionitis
Levels of S100A12 in Maternal, Cord and Neonatal Blood in the Presence or Absence of HCA
Time frame: 1 Year
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
The record gives a start of Feb 2012, a primary completion of Feb 2013 and a completion of Mar 2013. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Dec 2016. You cannot join it, but the record below documents what was studied.
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Catholic University of the Sacred Heart →