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CompletedNCT02905747Updated Mar 11, 2019

The Effect of Medical Exercise Therapy on Pain, Function and Physical Activity in Patients With Knee Osteoarthritis

An interventional study of Medical Exercise Therapy in Osteoarthritis, Knee, sponsored by Norwegian University of Science and Technology. Completed at 1 site in Norway. Open to participants aged 45 Years to 85 Years. Per ClinicalTrials.gov, last updated 2019-03-11.

Sponsored by Norwegian University of Science and Technology · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
15
Allocation
Not applicable
Ages
45 Years to 85 Years
Sex
All
01

Study summary

The aim of the project is to investigate effects of medical exercise therapy (MET) on patients with knee osteoarthritis. MET is a common physical therapy intervention, and the project aim to strengthen the evidence of this intervention. An experimental cohort design is chosen, and 20 participants will be followed for 6 months. Assessments will be clinical tests, questionnaires and accelerometer measurements before, during, and after a 3 month period of exercise (3 days per week) with a physical therapist. The project will answer if a 3 month physical therapy intervention using MET causes changes in pain level, function and activity level for patients with knee osteoarthritis. In addition, it will investigate whether a single global endurance workout for 30 minutes will have an effect on pain level for these patients

02

Conditions studied

  • Osteoarthritis, Knee

Keywords

  • Exercise Therapy
  • Musculoskeletal Pain
  • Knee osteoarthritis
  • Physical Therapy Modalities
03

In context

Osteoarthritis, Knee

3,391 studies on the registry are indexed under Osteoarthritis, Knee; 628 are open to participants now.

This study's enrollment of 15 is below the median of 69 across 2,808 interventional studies indexed under Osteoarthritis, Knee.

Browse Osteoarthritis, Knee studies →

Lead sponsor

Norwegian University of Science and Technology is the lead sponsor of 494 studies on the registry; 48 are open to participants now.

Browse Norwegian University of Science and Technology studies →

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
45 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • x-ray verified knee osteoarthritis (Kellegren \& Lawrence grade I-III)
  • Loss of function and withstanding pain >3 months

Exclusion criteria

Exclusion Criteria:

  • physical therapy treatment during the last 3 months
  • knee injury
  • inflammatory arthritis
  • symptoms from the hip joints greater than the knee pain
  • planned knee surgery the next 6 months
  • heart and lung disorders or other health issues affecting the ability to complete the intervention
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
15 participants (actual)

Study arms

  • Experimental
    Medical Exercise Therapy

    Medical Exercise Therapy (MET) developed by Oddvar Holten

    Behavioral: Medical Exercise Therapy

Interventions

  • BehavioralMedical Exercise Therapy

    physiotherapy intervention with Medical exercise therapy (MET) during 3 months

06

What researchers measure

Primary outcomes

  1. pain

    visual analog scale

    Time frame: 6 months

  2. Activity level

    Accelerometer

    Time frame: 6 months

  3. Function

    30 second chair stand test

    Time frame: 6 months

07

Study locations

1 site
  • NTNU
    Trondheim, Norway
08

References and documents

Publications

  • Osteras H, Paulsberg F. The Effect of Medical Exercise Therapy on Pressure Sensitivity in Patients with Knee Osteoarthritis: A Cohort Pilot Study. Pain Ther. 2019 Jun;8(1):79-87. doi: 10.1007/s40122-019-0121-5. Epub 2019 Mar 30. PubMed 30929225 ↗

Individual participant data

Plan to share: Undecided

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Sep 2016 to primary completion in Dec 2018, 27 months.

Of 1,143 non-industry interventional studies with no phase under Osteoarthritis, Knee, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 36. This study's 27 months is above that.

Counting every sponsor, half of 1,285 studies reached it within 18 months; a quarter within 8 and three quarters within 36.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 14, 2016
First posted
Sep 19, 2016
StartActual
Sep 2016
Primary completionActual
Dec 1, 2018
CompletionActual
Dec 1, 2018
Last update
Mar 11, 2019
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 11, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02905747
Lead sponsor
Norwegian University of Science and Technology
Responsible party
Sponsor
First posted
Sep 19, 2016
Start date
Sep 2016
Primary completion
Dec 1, 2018
Completion
Dec 1, 2018
Last update
Mar 11, 2019

Study contacts

Håvard Østerås, phd
principal investigator · Norwegian University of Science and Technology

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.

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