An interventional study of Simultaneous music and reading lyrics and Priming with music in Aphasia, sponsored by Carilion Clinic. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-09-20.
Sponsored by Carilion Clinic · Not applicable, Interventional, and Treatment
This investigation uses a single-subject, adapted alternating research design to compare two different experimental conditions using music with lyrics combined with visual stimulation of the written lyrics, to extend the emotional word effect to phrases, in order to stimulate reading comprehension of the trained material for patients with aphasia. The two music conditions include 1) music with sung lyrics simultaneously with silent reading of the written lyrics; and 2) music with sung lyrics, followed by silent reading of the written lyrics (i.e. priming with the music). A control set without music will be used additionally within every third session to detect potential history and maturation effects. All conditions will be followed by a silent reading phrase-completion task composed of written words from the total combined sets of stimuli.
The purpose of this investigation is to examine the evidence on emotion, language, and music, and propose a first step, in the form of a single-subject research design, to determine the most effective and efficient method for application to the rehabilitation of patients with aphasia. A single-subject adapted alternating treatment design will be used to compare two music conditions, using music with sung lyrics simultaneously with silent reading of the lyrics, and priming with music and sung lyrics followed by reading of the lyrics, with a control condition using reading materials without music. Risks are expected to be minimal. The risk is confidentiality. Risk management procedures in this study include: assuring confidentiality of participants, assuring qualified personnel, assuring convenient location, ensuring adequate enrollment, continual monitoring, addressing potential conflicts of interest, and making a plan to manage problems. Continual monitoring will be used to assess whether study interventions appear to be interfering with normal speech therapy treatment. If the researcher sees any signs of interference, the subject will be withdrawn from the research and study interventions will be stopped.
365 studies on the registry are indexed under Aphasia; 89 are open to participants now.
This study's enrollment of 1 is below the median of 30 across 316 interventional studies indexed under Aphasia.
Browse Aphasia studies →Carilion Clinic is the lead sponsor of 71 studies on the registry; 13 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 2 (22%) have results posted.
Counted across the registry records on this site, refreshed daily.
Capacity to provide informed consent concerning a study involving an intervention with music therapy: determined by the physician who refers the patient.
Exclusion Criteria:
A single-subject adapted alternating treatment design will be used to compare two music conditions, using music with sung lyrics simultaneously with silent reading of the lyrics, and priming with music and sung lyrics followed by reading of the lyrics, with a control condition using reading materials without music.
Behavioral: Simultaneous music and reading lyrics · Behavioral: Priming with music · Behavioral: Control
music with sung lyrics simultaneously with silent reading of the lyrics.
priming with music and sung lyrics followed by reading of the lyrics.
control condition using reading materials without music.
Percent correct responses per day on phrase completion task.
Differential response to the interventions (counted as the percent correct responses per day.
Time frame: through study completion, an average of 1 year
Number of sessions required to achieve mastery.
count number of sessions.
Time frame: through study completion, an average of 1 year
Retention of the reading material
Number of items recalled.
Time frame: 3 weeks post-intervention.
International Classification of Functioning, Disability, and Health (ICF) Body Functions/Structures, Activities, and Participation
Pretest/post-test information on the ICF Body Functions/Structures, Activities, and Participation (Hurkmans et al. 2011).
Time frame: through study completion, an average of 1 year
Boston Diagnostic Aphasia Examination-Third Edition (BDAE-3)
The Boston Diagnostic Aphasia Examination-Third Edition (BDAE-3) (Goodglass, Harold, \& Barresi, Austin: PRO-Ed.): Pretest reading scores on the BDAE full version subtests, i.e. B. Word Identification: 1. Word-Picture Match, and 2. Lexical Decision; C. 1. Homophone Matching; D. Derivational and Grammatical Morphology: 1. Matching to spoken sample; E. Oral Reading: 1. Basic oral word reading; F. Oral Reading of Sentences with Comprehension; and G. Reading Comprehension-Sentences and Paragraphs; will be completed prior to baseline A and initiating intervention, and immediately following completion of intervention to assess generalization to non-trained stimuli.
Time frame: through study completion, an average of 1 year
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Plan to share: No
This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.
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